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	<title>DEFINITIVE MIND</title>
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	<link>http://www.definitivemind.com</link>
	<description>Optimizing Mental and Physical Health through the Fusion of Knowledge and Skills from Neuroscience, Psychology, Psychiatry, Neuroendocrinology, Psychoneuroimmunology, Biochemistry, Nutritional Science and Other Fields in Art, Medicine, Philosophy, Science and Technology.  By Romeo Mariano MD</description>
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		<title>Blocking Pro-inflammatory Tumor Necrosis Factor with Remicade for Treatment-Resistant Depression</title>
		<link>http://www.definitivemind.com/2012/11/08/blocking-pro-inflammatory-tumor-necrosis-factor-with-remicade-for-treatment-resistant-depression/</link>
		<comments>http://www.definitivemind.com/2012/11/08/blocking-pro-inflammatory-tumor-necrosis-factor-with-remicade-for-treatment-resistant-depression/#comments</comments>
		<pubDate>Thu, 08 Nov 2012 18:41:54 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Cardiovascular]]></category>
		<category><![CDATA[Cytokines]]></category>
		<category><![CDATA[Depression]]></category>
		<category><![CDATA[FEATURED]]></category>
		<category><![CDATA[Inflammation]]></category>
		<category><![CDATA[Medications]]></category>
		<category><![CDATA[Mood Disorders]]></category>
		<category><![CDATA[Psychoneuro-immunology]]></category>
		<category><![CDATA[biologic medications]]></category>
		<category><![CDATA[cytokines]]></category>
		<category><![CDATA[depression]]></category>
		<category><![CDATA[inflammation]]></category>
		<category><![CDATA[tumor necrosis factor]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1220</guid>
		<description><![CDATA[Increased concentrations of inflammatory biomarkers predict antidepressant nonresponse, and inflammatory cytokines can sabotage and circumvent the mechanisms of action of conventional antidepressants. A drug that targets inflammation may assist in the treatment of depression in individuals with high levels of inflammation.  Results of a proof-of-concept study by him, Charles Raison, M.D., an associate professor of psychiatry at the University of Arizona, and colleagues showed that a biologic medication was able to reduce depressive symptoms in some subjects who had suffered from major depression for an average of 15 years.]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/11/08/blocking-pro-inflammatory-tumor-necrosis-factor-with-remicade-for-treatment-resistant-depression/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Screening For Depression In Patients With Diabetes</title>
		<link>http://www.definitivemind.com/2012/10/27/screening-for-depression-in-patients-with-diabetes/</link>
		<comments>http://www.definitivemind.com/2012/10/27/screening-for-depression-in-patients-with-diabetes/#comments</comments>
		<pubDate>Sat, 27 Oct 2012 20:03:08 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Depression]]></category>
		<category><![CDATA[Diabetes]]></category>
		<category><![CDATA[Neuro-endocrinology]]></category>
		<category><![CDATA[depression]]></category>
		<category><![CDATA[diabetes]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1217</guid>
		<description><![CDATA[The prevalence of depression is increased in people with diabetes and there are both national and international recommendations for screening of depression in people with diabetes. Most screening is currently sporadic and there are no formal screening programs. Further research is needed to evaluate the most clinically effective and cost effective way of doing so in structured screening programs.]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/10/27/screening-for-depression-in-patients-with-diabetes/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Citalopram, QTc Interval Prolongation, and Torsade de Pointes</title>
		<link>http://www.definitivemind.com/2012/10/15/citalopram-qtc-interval-prolongation-and-torsade-de-pointes/</link>
		<comments>http://www.definitivemind.com/2012/10/15/citalopram-qtc-interval-prolongation-and-torsade-de-pointes/#comments</comments>
		<pubDate>Mon, 15 Oct 2012 14:37:58 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Cardiovascular]]></category>
		<category><![CDATA[Medications]]></category>
		<category><![CDATA[Study Design Limitations]]></category>
		<category><![CDATA[citalopram]]></category>
		<category><![CDATA[QTc]]></category>
		<category><![CDATA[torsade de pointes]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1214</guid>
		<description><![CDATA[Recently, both the manufacturer of citalopram and the US Food and Drug Administration have warned health care providers and patients about new information implicating drug-induced QTc interval prolongation and torsade de pointes when using citalopram in doses >40 mg/day. This warning is not placed in the context of either benefits or risks in real-world clinical practice, leaving clinicians with an untenable choice between depriving patients of high-dose citalopram or malpractice litigation. We reviewed the literature and found no cases of citalopram-induced sudden cardiac death among patients taking up to 60 mg/day of citalopram and free of risk factors for QTc interval prolongation and torsade de pointes. Because psychotropic drug-induced sudden cardiac death is an outlier in the absence of identified risk factors for QTc interval prolongation and torsade de pointes, we do not believe current Phase 3 and Phase 4 studies provide sufficient information to limit current prescribing practices for citalopram (20 mg to 60 mg/day).]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/10/15/citalopram-qtc-interval-prolongation-and-torsade-de-pointes/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Sympathetic Overactivation Increases Inflammatory Immune Markers.</title>
		<link>http://www.definitivemind.com/2012/10/14/sympathetic-overactivation-increases-inflammatory-immune-markers/</link>
		<comments>http://www.definitivemind.com/2012/10/14/sympathetic-overactivation-increases-inflammatory-immune-markers/#comments</comments>
		<pubDate>Mon, 15 Oct 2012 03:19:23 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Inflammation]]></category>
		<category><![CDATA[Neurotransmitters]]></category>
		<category><![CDATA[Psychoneuro-immunology]]></category>
		<category><![CDATA[adrenergic receptor]]></category>
		<category><![CDATA[c-reactive protein]]></category>
		<category><![CDATA[cytokines]]></category>
		<category><![CDATA[sympathetic nervous system]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1211</guid>
		<description><![CDATA[Several stress-related states and conditions that are considered to involve sympathetic overactivation are accompanied by increased circulating levels of inflammatory immune markers. &#946;-AR sensitivity was lower in people with higher C-reactive protein concentration receiving Isoproterenol. This study demonstrates a link between in vivo &#946;-adrenergic receptor function and selected circulating inflammatory markers (CRP) in humans.]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/10/14/sympathetic-overactivation-increases-inflammatory-immune-markers/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Low-Dose Aripiprazole in the Treatment of SSRI-Induced Bruxism.</title>
		<link>http://www.definitivemind.com/2012/10/14/low-dose-aripiprazole-in-the-treatment-of-ssri-induced-bruxism/</link>
		<comments>http://www.definitivemind.com/2012/10/14/low-dose-aripiprazole-in-the-treatment-of-ssri-induced-bruxism/#comments</comments>
		<pubDate>Sun, 14 Oct 2012 21:40:48 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Gastroenterology]]></category>
		<category><![CDATA[Medications]]></category>
		<category><![CDATA[Neurology]]></category>
		<category><![CDATA[Neurotransmitters]]></category>
		<category><![CDATA[Pharmacology]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1207</guid>
		<description><![CDATA[Bruxism is characterized by involuntary, repetitive movements of jaw-clenching and teeth-grinding. Several reports in the literature suggest that selective serotonin reuptake inhibitors (SSRIs) might induce bruxism. In that event, clinicians face difficult treatment decisions, especially in cases whereby SSRIs cannot be discontinued or decreased, as in obsessive-compulsive disorder (OCD). In the following, we report the case of a patient with severe OCD and SSRI-induced bruxism successfully treated with low-dose aripiprazole.]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/10/14/low-dose-aripiprazole-in-the-treatment-of-ssri-induced-bruxism/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Metformin Prevents and Reverses Inflammation in a Non-Diabetic Nonalcoholic Fatty Liver Disease</title>
		<link>http://www.definitivemind.com/2012/10/14/metformin-prevents-and-reverses-inflammation-in-a-non-diabetic-nonalcoholic-fatty-liver-disease/</link>
		<comments>http://www.definitivemind.com/2012/10/14/metformin-prevents-and-reverses-inflammation-in-a-non-diabetic-nonalcoholic-fatty-liver-disease/#comments</comments>
		<pubDate>Sun, 14 Oct 2012 21:36:48 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Endocrinology]]></category>
		<category><![CDATA[Gastroenterology]]></category>
		<category><![CDATA[Inflammation]]></category>
		<category><![CDATA[Medications]]></category>
		<category><![CDATA[Neuro-endocrinology]]></category>
		<category><![CDATA[Psychoneuro-immunology]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1204</guid>
		<description><![CDATA[Metformin prevented and reversed steatosis and inflammation of NASH in an experimental non-diabetic model without affecting peripheral insulin resistance. Administration of metformin significantly decreased fasting plasma glucose levels, but did not affect glucose tolerance or peripheral insulin sensitivity. Metformin ameliorated MCD+HF diet-induced hepatic steatosis, inflammation, and fibrosis. Furthermore, metformin significantly reversed hepatic steatosis and inflammation when administered after the development of experimental NASH. These histological changes were accompanied by reduced hepatic triglyceride content, suppressed hepatic stellate cell activation, and the downregulation of genes involved in fatty acid metabolism, inflammation, and fibrogenesis.]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/10/14/metformin-prevents-and-reverses-inflammation-in-a-non-diabetic-nonalcoholic-fatty-liver-disease/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Astrocytes Use ATP as a Signal to Regulate Synaptic Plasticity Of Neural Circuits</title>
		<link>http://www.definitivemind.com/2012/10/14/astrocytes-use-atp-as-a-signal-to-regulate-synaptic-plasticity-of-neural-circuits/</link>
		<comments>http://www.definitivemind.com/2012/10/14/astrocytes-use-atp-as-a-signal-to-regulate-synaptic-plasticity-of-neural-circuits/#comments</comments>
		<pubDate>Sun, 14 Oct 2012 20:21:24 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Biology]]></category>
		<category><![CDATA[FEATURED]]></category>
		<category><![CDATA[Hypertension]]></category>
		<category><![CDATA[Medications]]></category>
		<category><![CDATA[Metabolism]]></category>
		<category><![CDATA[Neurobiology]]></category>
		<category><![CDATA[Neuroplasticity]]></category>
		<category><![CDATA[Neurotransmitters]]></category>
		<category><![CDATA[Psychiatry]]></category>
		<category><![CDATA[astrocyte]]></category>
		<category><![CDATA[atp]]></category>
		<category><![CDATA[featured]]></category>
		<category><![CDATA[glia]]></category>
		<category><![CDATA[neuroplasticity]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1201</guid>
		<description><![CDATA[Astrocytes actively participate in activity-dependent synaptic plasticity of neural circuits. Astrocyte activation is both necessary and sufficient for mediating hLTD accompanying LTP induction.  Heterosynaptic long-term depression (hLTD) at synapses accompanying the induction of long-term potentiation (LTP) spatially sharpens the activity-induced synaptic potentiation. Heterosynaptic long-term depression in the hippocampal CA1 region is caused by stimulation-induced ATP release from astrocytes that suppresses transmitter release from synaptic terminals via activation of P2Y receptors. Selective stimulation of astrocytes resulted in LTD of synapses on neighboring neurons. This synaptic modification required Ca(2+) elevation in astrocytes and activation of P2Y receptors, but not N-methyl-D-aspartate receptors.  Blocking P2Y receptors or buffering astrocyte intracellular Ca(2+) at a low level prevented hLTD without affecting LTP]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/10/14/astrocytes-use-atp-as-a-signal-to-regulate-synaptic-plasticity-of-neural-circuits/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Unpredictable Chronic Mild Stress Promotes Atherosclerosis</title>
		<link>http://www.definitivemind.com/2012/10/14/unpredictable-chronic-mild-stress-promotes-atherosclerosis/</link>
		<comments>http://www.definitivemind.com/2012/10/14/unpredictable-chronic-mild-stress-promotes-atherosclerosis/#comments</comments>
		<pubDate>Sun, 14 Oct 2012 19:24:09 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Cardiovascular]]></category>
		<category><![CDATA[Neuro-endocrinology]]></category>
		<category><![CDATA[Pathophysiology]]></category>
		<category><![CDATA[Psychoneuro-immunology]]></category>
		<category><![CDATA[atherosclerosis]]></category>
		<category><![CDATA[stress]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1198</guid>
		<description><![CDATA[Chronic psychological stress may contribute to the development of atherosclerosis by enhancing vascular inflammation and decreasing endothelial nitric oxide bioavailability. Unpredictable chronic mild stress (UCMS) exposure significantly increased the plaque size (p = .003) and decreased the plaque stability (decreased the contents of collagen and smooth muscle and increased the amount of macrophage and matrix metalloproteinases). The proatherogenic effects of UCMS were unrelated to changes in serum cholesterol level but accompanied by increased blood pressure (p < .001) and vascular inflammation (up-regulation of tumor necrosis factor &#945;, C-reactive protein, and monocyte chemoattractant protein 1, all p values < .01). Serum concentrations of nitrate/nitrite were lower in UCMS-treated animals (p = .01). Vessels from UCMS-treated animals exhibited augmented phosphorylation of p38 and c-Jun N-terminal kinase and activation of nuclear factor &#954;B.]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/10/14/unpredictable-chronic-mild-stress-promotes-atherosclerosis/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Vitamin D, Dyslipidemia, and Metabolic Syndrome in Rheumatoid Arthritis.</title>
		<link>http://www.definitivemind.com/2012/10/14/vitamin-d-dyslipidemia-and-metabolic-syndrome-in-rheumatoid-arthritis/</link>
		<comments>http://www.definitivemind.com/2012/10/14/vitamin-d-dyslipidemia-and-metabolic-syndrome-in-rheumatoid-arthritis/#comments</comments>
		<pubDate>Sun, 14 Oct 2012 19:11:07 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Cardiovascular]]></category>
		<category><![CDATA[Endocrinology]]></category>
		<category><![CDATA[Hormones]]></category>
		<category><![CDATA[Immunology]]></category>
		<category><![CDATA[Pathophysiology]]></category>
		<category><![CDATA[Vitamins, Minerals and Other Nutrients]]></category>
		<category><![CDATA[dyslipidemia]]></category>
		<category><![CDATA[metabolic syndrome]]></category>
		<category><![CDATA[rheumatoid arthritis]]></category>
		<category><![CDATA[vitamin D]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1195</guid>
		<description><![CDATA[Vitamin D deficiency is a potential risk factor for cardiometabolic disease. Vitamin D deficiency was associated with the metabolic syndrome and dyslipidemia. Vitamin D levels (per 10 ng/mL) were associated inversely with low-density lipoprotein (&#946;: -0.029 [-0.049, -0.0091], P=.004) and triglyceride (&#946;: -0.094 [-0.15, -0.039] P=.001) levels. Vitamin D deficiency was associated independently with an increased odds of hyperlipidemia (odds ratio 1.72; 95% confidence interval, 1.10-2.45; P=.014) and metabolic syndrome (odds ratio 3.45; 95% confidence interval, 1.75-6.80; P <.001) in adjusted models.]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/10/14/vitamin-d-dyslipidemia-and-metabolic-syndrome-in-rheumatoid-arthritis/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Abdominal Migraine</title>
		<link>http://www.definitivemind.com/2012/10/14/abdominal-migraine/</link>
		<comments>http://www.definitivemind.com/2012/10/14/abdominal-migraine/#comments</comments>
		<pubDate>Sun, 14 Oct 2012 18:59:30 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Gastroenterology]]></category>
		<category><![CDATA[Neurology]]></category>
		<category><![CDATA[Pain]]></category>
		<category><![CDATA[abdominal migraine]]></category>
		<category><![CDATA[migraine]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1190</guid>
		<description><![CDATA[Abdominal migraine is a diagnostically challenging disorder, characterized by recurrent episodes of abdominal pain. Our findings demonstrate that abdominal migraine occurs and should be considered in the differential diagnosis of recurrent abdominal pain in adults, especially if there is a family history of migraine headaches.]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/10/14/abdominal-migraine/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Growth Hormone-Releasing Hormone improves Cognition in Older Adults and Adults with  Mild Cognitive Impairment</title>
		<link>http://www.definitivemind.com/2012/10/13/growth-hormone-releasing-hormone-improves-cognition-in-older-adults-and-adults-with-mild-cognitive-impairment/</link>
		<comments>http://www.definitivemind.com/2012/10/13/growth-hormone-releasing-hormone-improves-cognition-in-older-adults-and-adults-with-mild-cognitive-impairment/#comments</comments>
		<pubDate>Sat, 13 Oct 2012 20:35:42 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Cognitive Disorders and Dementia]]></category>
		<category><![CDATA[Endocrinology]]></category>
		<category><![CDATA[FEATURED]]></category>
		<category><![CDATA[Hormones]]></category>
		<category><![CDATA[Medications]]></category>
		<category><![CDATA[Neuro-endocrinology]]></category>
		<category><![CDATA[Neuroplasticity]]></category>
		<category><![CDATA[Obesity]]></category>
		<category><![CDATA[Psychiatry]]></category>
		<category><![CDATA[alzheimer's disease]]></category>
		<category><![CDATA[featured]]></category>
		<category><![CDATA[GHRH]]></category>
		<category><![CDATA[growth hormone]]></category>
		<category><![CDATA[growth-hormone releasing-hormone]]></category>
		<category><![CDATA[IGF-1]]></category>
		<category><![CDATA[insulin]]></category>
		<category><![CDATA[mild cognitive impairment]]></category>
		<category><![CDATA[obesity]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1175</guid>
		<description><![CDATA[Growth hormone-releasing hormone (GHRH), growth hormone, and insulinlike growth factor 1 have potent effects on brain function, their levels decrease with advancing age, and they likely play a role in the pathogenesis of Alzheimer disease. Previously, we reported favorable cognitive effects of short-term GHRH administration in healthy older adults and provided preliminary evidence to suggest a similar benefit in adults with mild cognitive impairment (MCI). The intent-to-treat analysis indicated a favorable effect of GHRH on cognition which was comparable in adults with MCI and healthy older adults. Subsequent analyses indicated a positive GHRH effect on executive function and a trend showing a similar treatment-related benefit in verbal memory. Treatment with GHRH increased insulinlike growth factor 1 levels by 117%, which remained within the physiological range, and reduced percent body fat by 7.4%. Treatment with GHRH increased fasting insulin levels within the normal range by 35% in adults with MCI but not in healthy adults. Adverse events were mild and were reported by 68% of GHRH-treated adults and 36% of those who received placebo.]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/10/13/growth-hormone-releasing-hormone-improves-cognition-in-older-adults-and-adults-with-mild-cognitive-impairment/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Thioridazine Inhibits Peroxisomal &#946;-oxidation, Leading to Increased Very Long Chain Fatty Acids and Beta-Amyloid Peptide and an Increased Risk of Alzheimer&#8217;s Disease</title>
		<link>http://www.definitivemind.com/2012/10/10/thioridazine-inhibits-peroxisomal-oxidation-leading-to-increased-very-long-chain-fatty-acids-and-beta-amyloid-peptide-and-an-increased-risk-of-alzheimers-disease/</link>
		<comments>http://www.definitivemind.com/2012/10/10/thioridazine-inhibits-peroxisomal-oxidation-leading-to-increased-very-long-chain-fatty-acids-and-beta-amyloid-peptide-and-an-increased-risk-of-alzheimers-disease/#comments</comments>
		<pubDate>Wed, 10 Oct 2012 09:13:19 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Cognitive Disorders and Dementia]]></category>
		<category><![CDATA[FEATURED]]></category>
		<category><![CDATA[Neurobiology]]></category>
		<category><![CDATA[Psychiatry]]></category>
		<category><![CDATA[Psychosis]]></category>
		<category><![CDATA[Alzheimer Disease]]></category>
		<category><![CDATA[Antipsychotics]]></category>
		<category><![CDATA[beta-amyloid]]></category>
		<category><![CDATA[beta-oxidation]]></category>
		<category><![CDATA[dementia]]></category>
		<category><![CDATA[fatty acids]]></category>
		<category><![CDATA[featured]]></category>
		<category><![CDATA[thioridazine]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1169</guid>
		<description><![CDATA[Alzheimer's disease (AD) is characterized by the accumulation of the &#946;-amyloid peptide (A&#946;), which is generated from sequential cleavages of the amyloid precursor protein (APP) by &#946;-secretase (BACE1) and &#947;-secretase. Increased very long chain fatty acid (VLCFA) levels in AD brains imply that peroxisomal &#946;-oxidation dysfunction may be associated with AD pathogenesis. Thioridazine is a selective peroxisomal &#946;-oxidation inhibitor. Thioridazine caused VLCFA accumulation and increases in A&#946;(40) content, APP immunoreactivity and APP(751+770) mRNA expressions in the rat cerebral cortex. Impaired peroxisomal function may play an important role in the progression of AD pathology.]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/10/10/thioridazine-inhibits-peroxisomal-oxidation-leading-to-increased-very-long-chain-fatty-acids-and-beta-amyloid-peptide-and-an-increased-risk-of-alzheimers-disease/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Graves Disease Review</title>
		<link>http://www.definitivemind.com/2012/10/08/graves-disease-review/</link>
		<comments>http://www.definitivemind.com/2012/10/08/graves-disease-review/#comments</comments>
		<pubDate>Mon, 08 Oct 2012 23:17:27 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Endocrinology]]></category>
		<category><![CDATA[Immunology]]></category>
		<category><![CDATA[Psychoneuro-immunology]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1166</guid>
		<description><![CDATA[Autoimmune thyrotoxicosis or Graves' disease (GD) is the most common cause of hyperthyroidism in the United States. GD occurs more often in women (ratio 5:1) and has a population prevalence of 1-2%. GD is a systemic autoimmune thyroid disorder characterized by the infiltration of immune effector cells and thyroid-antigen-specific T cells into the thyroid and thyroid stimulating hormone receptor (TSHR) expressing tissues, i.e. orbit, skin, with the production of autoantibodies to well-defined thyroidal antigens. Diagnosis of GD is straightforward in a patient with a diffusely enlarged, heterogeneous, hypervascular (increased Doppler flow on neck ultrasound) thyroid gland, associated orbitopathy, biochemically confirmed thyrotoxicosis, positive TSHR autoantibodies, and often a family history of autoimmune disorders.]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/10/08/graves-disease-review/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>SSRI-Use vs. Non-Use for Depression During Pregnancy</title>
		<link>http://www.definitivemind.com/2012/10/08/ssri-use-vs-non-use-for-depression-during-pregnancy/</link>
		<comments>http://www.definitivemind.com/2012/10/08/ssri-use-vs-non-use-for-depression-during-pregnancy/#comments</comments>
		<pubDate>Mon, 08 Oct 2012 15:38:55 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Depression]]></category>
		<category><![CDATA[Medications]]></category>
		<category><![CDATA[depression]]></category>
		<category><![CDATA[pregnancy]]></category>
		<category><![CDATA[SSRI]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1163</guid>
		<description><![CDATA[Untreated maternal depression was associated with slower rates of fetal body and head growth. Pregnant mothers treated with SSRIs had fewer depressive symptoms and their fetuses had no delay in body growth but had delayed head growth and were at increased risk for preterm birth.]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/10/08/ssri-use-vs-non-use-for-depression-during-pregnancy/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Higher Levels of Adipocytokines Increase the Risk for Stroke</title>
		<link>http://www.definitivemind.com/2012/10/06/higher-levels-of-adipocytokines-increase-the-risk-for-stroke/</link>
		<comments>http://www.definitivemind.com/2012/10/06/higher-levels-of-adipocytokines-increase-the-risk-for-stroke/#comments</comments>
		<pubDate>Sun, 07 Oct 2012 06:53:55 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Cardiovascular]]></category>
		<category><![CDATA[Cytokines]]></category>
		<category><![CDATA[Obesity]]></category>
		<category><![CDATA[adipocytokines]]></category>
		<category><![CDATA[adiponectin]]></category>
		<category><![CDATA[adipsin]]></category>
		<category><![CDATA[leptin]]></category>
		<category><![CDATA[obesity]]></category>
		<category><![CDATA[resistin]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1152</guid>
		<description><![CDATA[Higher plasma levels of resistin, adipsin, and total adiponectin were associated with an increased 10-year risk of ischemic stroke among healthy middle-aged men.  Resistin, adipsin, and total adiponectin, but not leptin, were independent predictors of ischemic stroke. The performance of a traditional risk factor model predicting ischemic stroke was significantly improved by the simultaneous inclusion of resistin, adipsin, and total adiponectin.]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/10/06/higher-levels-of-adipocytokines-increase-the-risk-for-stroke/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Inflammatory prostaglandin E(2)  Signaling on EP3 Receptors Lead to Pro-inflammatory Changes Contributing to Alzheimer&#8217;s Disease</title>
		<link>http://www.definitivemind.com/2012/10/06/inflammatory-prostaglandin-e2-signaling-on-ep3-receptors-lead-to-pro-inflammatory-changes-contributing-to-alzheimers-disease/</link>
		<comments>http://www.definitivemind.com/2012/10/06/inflammatory-prostaglandin-e2-signaling-on-ep3-receptors-lead-to-pro-inflammatory-changes-contributing-to-alzheimers-disease/#comments</comments>
		<pubDate>Sun, 07 Oct 2012 04:18:10 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Cognitive Disorders and Dementia]]></category>
		<category><![CDATA[Cytokines]]></category>
		<category><![CDATA[Inflammation]]></category>
		<category><![CDATA[Medications]]></category>
		<category><![CDATA[Neuro-endocrinology]]></category>
		<category><![CDATA[Alzheimer Disease]]></category>
		<category><![CDATA[cytokines]]></category>
		<category><![CDATA[inflammation]]></category>
		<category><![CDATA[Prostaglandin]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1149</guid>
		<description><![CDATA[There is significant evidence for a central role of inflammation in the development of Alzheimer disease (AD). Chronic use of nonsteroidal anti-inflammatory drugs (NSAIDs) reduces the risk of developing AD. Stimulation of the the PGE(2) EP3 receptor activates proinflammatory, proamyloidogenic, and synaptotoxic signaling pathways. Deletion of the PGE(2) EP3 receptor in a model of A&#946;(42) peptide-induced neuroinflammation reduced proinflammatory gene expression, cytokine production, and oxidative stress. Deletion of the EP3 receptor blocked induction of proinflammatory gene and protein expression and lipid peroxidation,  and levels of A&#946; peptides were significantly decreased, as were &#946;-secretase and &#946; C-terminal fragment levels.]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/10/06/inflammatory-prostaglandin-e2-signaling-on-ep3-receptors-lead-to-pro-inflammatory-changes-contributing-to-alzheimers-disease/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Psychoneuroimmunology of Psoriasis</title>
		<link>http://www.definitivemind.com/2012/10/06/psychoneuroimmunology-of-psoriasis/</link>
		<comments>http://www.definitivemind.com/2012/10/06/psychoneuroimmunology-of-psoriasis/#comments</comments>
		<pubDate>Sun, 07 Oct 2012 04:06:09 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Dermatology]]></category>
		<category><![CDATA[Immunology]]></category>
		<category><![CDATA[Psychoneuro-immunology]]></category>
		<category><![CDATA[psoriasis]]></category>
		<category><![CDATA[psychoneuroimmunology]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1146</guid>
		<description><![CDATA[Bi-directional communication between the Central Nervous System and the Endocrine System has been known for many years. Some of the hormones, themselves, are secreted by the Brain. The CNS and Endocrine System are also involved in a bi-directional communication with the Immune System. This has been a target of intense research in recent decades. Psychological states are related to changes in immune meidators. These influence the development of diseases. This review looks at the role of psychoneuroimmunology in psoriasis.]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/10/06/psychoneuroimmunology-of-psoriasis/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Stress Activates Immune System Pro-inflammatory Changes Contributing to Coronary Artery Disease</title>
		<link>http://www.definitivemind.com/2012/10/06/research-on-psychoneuroimmunology-does-stress-influence-immunity-and-cause-coronary-artery-disease/</link>
		<comments>http://www.definitivemind.com/2012/10/06/research-on-psychoneuroimmunology-does-stress-influence-immunity-and-cause-coronary-artery-disease/#comments</comments>
		<pubDate>Sun, 07 Oct 2012 03:57:02 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Cardiovascular]]></category>
		<category><![CDATA[Psychology]]></category>
		<category><![CDATA[Psychoneuro-immunology]]></category>
		<category><![CDATA[coronary artery disease]]></category>
		<category><![CDATA[immune system]]></category>
		<category><![CDATA[stress]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1141</guid>
		<description><![CDATA[The evidence for the effects of acute and chronic psychological stress on the onset and progression of CAD is consistent and convincing. Psychological stressors change endothelial function and lead to chemotaxis. Acute psychological stressors lead to leukocytosis, increased natural killer cell cytotoxicity and reduced proliferative response to mitogens. Psychological stressors will increase haemostatic factors and acute phase proteins, possibly leading to thrombus formation and myocardial infarction.]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/10/06/research-on-psychoneuroimmunology-does-stress-influence-immunity-and-cause-coronary-artery-disease/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Obesity results in chronic low-grade pro-inflammatory signaling that contributes to anxiety and depressive behaviors</title>
		<link>http://www.definitivemind.com/2012/10/01/relationship-between-adiposity-emotional-status-and-eating-behaviour-in-obese-women-role-of-inflammation/</link>
		<comments>http://www.definitivemind.com/2012/10/01/relationship-between-adiposity-emotional-status-and-eating-behaviour-in-obese-women-role-of-inflammation/#comments</comments>
		<pubDate>Tue, 02 Oct 2012 04:28:39 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Anxiety Disorders]]></category>
		<category><![CDATA[Cytokines]]></category>
		<category><![CDATA[Depression]]></category>
		<category><![CDATA[Obesity]]></category>
		<category><![CDATA[Psychoneuro-immunology]]></category>
		<category><![CDATA[anxiety]]></category>
		<category><![CDATA[cytokines]]></category>
		<category><![CDATA[depression]]></category>
		<category><![CDATA[inflammation]]></category>
		<category><![CDATA[obesity]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1128</guid>
		<description><![CDATA[Obesity is characterized by chronic low-grade inflammation that may lead to emotional distress and behavioural symptoms. At baseline, body mass index (BMI) was positively correlated with inflammatory markers and adipokines. Regression analyses adjusting for age and diabetes revealed that baseline concentrations of IL-6 and hsCRP were associated with the depression and anxiety facets of neuroticism, with higher inflammation predicting higher anxiety and depression.]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/10/01/relationship-between-adiposity-emotional-status-and-eating-behaviour-in-obese-women-role-of-inflammation/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Insomnia Increases Pro-Inflammatory Signaling Contributing To Cardiovascular Disease</title>
		<link>http://www.definitivemind.com/2012/10/01/insomnia-increases-pro-inflammatory-signaling-which-contributes-to-cardiovascular-disease/</link>
		<comments>http://www.definitivemind.com/2012/10/01/insomnia-increases-pro-inflammatory-signaling-which-contributes-to-cardiovascular-disease/#comments</comments>
		<pubDate>Tue, 02 Oct 2012 03:27:15 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Cardiovascular]]></category>
		<category><![CDATA[Cytokines]]></category>
		<category><![CDATA[Neurobiology]]></category>
		<category><![CDATA[Pathophysiology]]></category>
		<category><![CDATA[Psychoneuro-immunology]]></category>
		<category><![CDATA[cardiovascular disease]]></category>
		<category><![CDATA[cytokines]]></category>
		<category><![CDATA[depression]]></category>
		<category><![CDATA[insomnia]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1125</guid>
		<description><![CDATA[Bidirectional communication between the brain and the immune system is carried out through a complex network of autonomic nerves, endocrine hormones, and cytokines. Insomnia perturbs the functioning of this network and therefore contribute to elevations in inflammatory mediators which lead to cardiovascular disease.]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/10/01/insomnia-increases-pro-inflammatory-signaling-which-contributes-to-cardiovascular-disease/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Insomnia exacerbates fatigue, depression, pain, and rheumatoid arthritis.</title>
		<link>http://www.definitivemind.com/2012/10/01/sleep-loss-exacerbates-fatigue-depression-and-pain-in-rheumatoid-arthritis/</link>
		<comments>http://www.definitivemind.com/2012/10/01/sleep-loss-exacerbates-fatigue-depression-and-pain-in-rheumatoid-arthritis/#comments</comments>
		<pubDate>Tue, 02 Oct 2012 03:21:04 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Anxiety Disorders]]></category>
		<category><![CDATA[Cytokines]]></category>
		<category><![CDATA[Depression]]></category>
		<category><![CDATA[Immunology]]></category>
		<category><![CDATA[Inflammation]]></category>
		<category><![CDATA[Neurobiology]]></category>
		<category><![CDATA[Psychoneuro-immunology]]></category>
		<category><![CDATA[depression]]></category>
		<category><![CDATA[fatigue]]></category>
		<category><![CDATA[pain]]></category>
		<category><![CDATA[rheumatoid arthritis]]></category>
		<category><![CDATA[sleep]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1120</guid>
		<description><![CDATA[This study provides the first evidence of an exaggerated increase in symptoms of mood and pain in patients with rheumatoid arthritis after sleep loss, along with an activation of rheumatoid arthritis-related joint pain. Given the reciprocal relationship between sleep disturbances and pain, clinical management of pain in patients with rheumatoid arthritis should include an increased focus on the prevention and treatment of sleep disturbance in this clinical population.]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/10/01/sleep-loss-exacerbates-fatigue-depression-and-pain-in-rheumatoid-arthritis/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Sulfasalazine Inhibits Activation of NF-&#954;B in Basolateral Amygdala, Impairing Memory Persistance in Auditory Fear Conditioning</title>
		<link>http://www.definitivemind.com/2012/09/18/sulfasalazine-inhibits-activation-of-nf-b-in-basolateral-amygdala-impairing-memory-persistance-in-auditory-fear-conditioning/</link>
		<comments>http://www.definitivemind.com/2012/09/18/sulfasalazine-inhibits-activation-of-nf-b-in-basolateral-amygdala-impairing-memory-persistance-in-auditory-fear-conditioning/#comments</comments>
		<pubDate>Wed, 19 Sep 2012 05:32:14 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Inflammation]]></category>
		<category><![CDATA[Medications]]></category>
		<category><![CDATA[Neurobiology]]></category>
		<category><![CDATA[Psychoneuro-immunology]]></category>
		<category><![CDATA[PTSD]]></category>
		<category><![CDATA[amygdala]]></category>
		<category><![CDATA[NF-kappB]]></category>
		<category><![CDATA[sulfasalazine]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1117</guid>
		<description><![CDATA[Activation of NF-&#954;B in Basolateral Amygdala Is Required for Memory Reconsolidation in Auditory Fear ConditioningPLoS One. 2012;7(9):e43973. Epub 2012 Sep 5.Si J, Yang J, Xue L, Yang C, Luo Y, Shi H, Lu L.Source Abstract Posttraumatic stress disorder (PTSD) is characterized by acute and chronic changes in the stress response, manifested as conditioned fear memory. [...]]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/09/18/sulfasalazine-inhibits-activation-of-nf-b-in-basolateral-amygdala-impairing-memory-persistance-in-auditory-fear-conditioning/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Rice Protein Reduces Oxidative Stress</title>
		<link>http://www.definitivemind.com/2012/09/12/rice-protein-reduces-oxidative-stress/</link>
		<comments>http://www.definitivemind.com/2012/09/12/rice-protein-reduces-oxidative-stress/#comments</comments>
		<pubDate>Wed, 12 Sep 2012 10:20:26 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Exercise]]></category>
		<category><![CDATA[Nutrition]]></category>
		<category><![CDATA[Vitamins, Minerals and Other Nutrients]]></category>
		<category><![CDATA[oxidative stress]]></category>
		<category><![CDATA[rice protein]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1113</guid>
		<description><![CDATA[Rice protein improves oxidative stress by regulating glutathione metabolism and attenuating oxidative damage to lipids and proteins in rats Life Sci. 2012 Aug 11; Yang L, Chen JH, Xu T, Zhou AS, Yang HK Abstract AIMS: To evaluate the effects of rice protein (RP) on glutathione metabolism and oxidative damage. MAIN METHODS: Seven-week-old male Wistar [...]]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/09/12/rice-protein-reduces-oxidative-stress/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>B Vitamins Can Reduce Pain</title>
		<link>http://www.definitivemind.com/2012/09/12/b-vitamins-can-reduce-pain/</link>
		<comments>http://www.definitivemind.com/2012/09/12/b-vitamins-can-reduce-pain/#comments</comments>
		<pubDate>Wed, 12 Sep 2012 10:07:42 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Neurology]]></category>
		<category><![CDATA[Vitamins, Minerals and Other Nutrients]]></category>
		<category><![CDATA[B Vitamins]]></category>
		<category><![CDATA[Neuropathic pain]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1110</guid>
		<description><![CDATA[B vitamins relieve neuropathic pain behaviors induced by infraorbital nerve constriction in rats Life Sci. 2012 Aug 24; Kopruszinski CM, Reis RC, Chichorro JG Abstract AIMS: There is mounting evidence that use of B vitamins can help control neuropathic pain. This study investigated if treatment with B1, B6 and B12 vitamins, alone or in combination [...]]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/09/12/b-vitamins-can-reduce-pain/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Obesity in Bipolar Disorder</title>
		<link>http://www.definitivemind.com/2012/09/11/obesity-in-bipolar-disorder/</link>
		<comments>http://www.definitivemind.com/2012/09/11/obesity-in-bipolar-disorder/#comments</comments>
		<pubDate>Wed, 12 Sep 2012 05:23:59 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Bipolar Disorder]]></category>
		<category><![CDATA[Neuro-endocrinology]]></category>
		<category><![CDATA[Neurobiology]]></category>
		<category><![CDATA[Pathophysiology]]></category>
		<category><![CDATA[bipolar disorder]]></category>
		<category><![CDATA[metabolism]]></category>
		<category><![CDATA[obesity]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1103</guid>
		<description><![CDATA[Obesity in Bipolar Disorder: An Overview Curr Psychiatry Rep. 2012 Aug 18; McElroy SL, Keck PE Abstract Bipolar disorder (BD) is associated with obesity, overweight, and abdominal obesity, and BD individuals with obesity have a greater illness burden. Factors related to BD, its treatment, and the individual may all contribute to BD&#8217;s association with obesity. [...]]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/09/11/obesity-in-bipolar-disorder/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Seroquel Reduces Autoimmune-Mediated Demyelination and IL-2</title>
		<link>http://www.definitivemind.com/2012/09/10/seroquel-reduces-autoimmune-mediated-demyelination-and-il-2/</link>
		<comments>http://www.definitivemind.com/2012/09/10/seroquel-reduces-autoimmune-mediated-demyelination-and-il-2/#comments</comments>
		<pubDate>Tue, 11 Sep 2012 07:10:18 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Cytokines]]></category>
		<category><![CDATA[Immunology]]></category>
		<category><![CDATA[Inflammation]]></category>
		<category><![CDATA[Medications]]></category>
		<category><![CDATA[Neurobiology]]></category>
		<category><![CDATA[Neurology]]></category>
		<category><![CDATA[Psychoneuro-immunology]]></category>
		<category><![CDATA[anti-inflammatory]]></category>
		<category><![CDATA[autoimmune]]></category>
		<category><![CDATA[Demyelination]]></category>
		<category><![CDATA[interleukin]]></category>
		<category><![CDATA[multiple sclerosis]]></category>
		<category><![CDATA[quetiapine]]></category>
		<category><![CDATA[Seroquel]]></category>
		<category><![CDATA[T-cell]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1096</guid>
		<description><![CDATA[Quetiapine, an Atypical Antipsychotic, Is Protective against Autoimmune-Mediated Demyelination by Inhibiting Effector T Cell Proliferation Feng Mei, Sheng Guo, Yangtao He, Linyun Wang, Hongkai Wang, Jianqin Niu, Jiming Kong, Xinmin Li, Yuzhang Wu, Lan Xiao PLoS One. 2012;7(8):e42746. Epub 2012 Aug 13. Abstract Quetiapine (Que), a commonly used atypical antipsychotic drug (APD), can prevent myelin [...]]]></description>
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		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Mental Fatigue Associated with Sympathetic Hyperactivity</title>
		<link>http://www.definitivemind.com/2012/09/09/mental-fatigue-associated-with-sympathetic-hyperactivity/</link>
		<comments>http://www.definitivemind.com/2012/09/09/mental-fatigue-associated-with-sympathetic-hyperactivity/#comments</comments>
		<pubDate>Mon, 10 Sep 2012 03:33:22 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Fatigue]]></category>
		<category><![CDATA[Neuro-endocrinology]]></category>
		<category><![CDATA[Neurotransmitters]]></category>
		<category><![CDATA[Psychosocial]]></category>
		<category><![CDATA[fatigue]]></category>
		<category><![CDATA[mental fatigue]]></category>
		<category><![CDATA[stress]]></category>
		<category><![CDATA[sympathetic nervous system]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1085</guid>
		<description><![CDATA[Mental fatigue caused by prolonged cognitive load associated with sympathetic hyperactivity Behav Brain Funct. 2011;7:17 Mizuno K, Tanaka M, Yamaguti K, Kajimoto O, Kuratsune H, Watanabe Y Abstract BACKGROUND: It is known that chronic fatigue is associated with sympathetic hyperactivity. However, the relationship between autonomic function and mental fatigue caused by a prolonged mental load [...]]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/09/09/mental-fatigue-associated-with-sympathetic-hyperactivity/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Testosterone is anti-inflammatory</title>
		<link>http://www.definitivemind.com/2012/09/08/testosterone-has-immune-modulating-properties-and-current-in-vitro-evidence-suggests-that-testosterone-may-suppress-the-expression-of-the-proinflammatory-cytokines-tnfalpha-il-1beta-and-il-6-and-po/</link>
		<comments>http://www.definitivemind.com/2012/09/08/testosterone-has-immune-modulating-properties-and-current-in-vitro-evidence-suggests-that-testosterone-may-suppress-the-expression-of-the-proinflammatory-cytokines-tnfalpha-il-1beta-and-il-6-and-po/#comments</comments>
		<pubDate>Sun, 09 Sep 2012 02:33:46 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Cardiovascular]]></category>
		<category><![CDATA[Depression]]></category>
		<category><![CDATA[FEATURED]]></category>
		<category><![CDATA[Immunology]]></category>
		<category><![CDATA[Inflammation]]></category>
		<category><![CDATA[Neuro-endocrinology]]></category>
		<category><![CDATA[Psychoneuro-immunology]]></category>
		<category><![CDATA[Sexual Health]]></category>
		<category><![CDATA[cardiovascular]]></category>
		<category><![CDATA[cytokines]]></category>
		<category><![CDATA[depression]]></category>
		<category><![CDATA[inflammation]]></category>
		<category><![CDATA[testosterone]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1074</guid>
		<description><![CDATA[The effect of testosterone replacement on endogenous inflammatory cytokines and lipid profiles in hypogonadal men J Clin Endocrinol Metab. 2004 Jul;89(7):3313-8 Malkin CJ, Pugh PJ, Jones RD, Kapoor D, Channer KS, Jones TH. Abstract Testosterone has immune-modulating properties, and current in vitro evidence suggests that testosterone may suppress the expression of the proinflammatory cytokines TNF-alpha, [...]]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/09/08/testosterone-has-immune-modulating-properties-and-current-in-vitro-evidence-suggests-that-testosterone-may-suppress-the-expression-of-the-proinflammatory-cytokines-tnfalpha-il-1beta-and-il-6-and-po/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
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		<title>Stress, food, and inflammation</title>
		<link>http://www.definitivemind.com/2012/09/05/stress-food-and-inflammation/</link>
		<comments>http://www.definitivemind.com/2012/09/05/stress-food-and-inflammation/#comments</comments>
		<pubDate>Thu, 06 Sep 2012 04:19:12 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Gastroenterology]]></category>
		<category><![CDATA[Inflammation]]></category>
		<category><![CDATA[Neuro-endocrinology]]></category>
		<category><![CDATA[Nutrition]]></category>
		<category><![CDATA[Psychoneuro-immunology]]></category>
		<category><![CDATA[inflammation]]></category>
		<category><![CDATA[stress]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1069</guid>
		<description><![CDATA[Stress, food, and inflammation: psychoneuroimmunology and nutrition at the cutting edge &#160;&#160; Psychosom Med. 2010 May;72(4):365-9 Kiecolt-Glaser JK Abstract Inflammation is the common link among the leading causes of death. Mechanistic studies have shown how various dietary components can modulate key pathways to inflammation, including sympathetic activity, oxidative stress, transcription factor nuclear factor-kappaB activation, and [...]]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/09/05/stress-food-and-inflammation/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Schizophrenia and anti-inflammatory therapy</title>
		<link>http://www.definitivemind.com/2012/09/05/schizophrenia-and-anti-inflammatory-therapy/</link>
		<comments>http://www.definitivemind.com/2012/09/05/schizophrenia-and-anti-inflammatory-therapy/#comments</comments>
		<pubDate>Wed, 05 Sep 2012 12:10:57 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Inflammation]]></category>
		<category><![CDATA[Psychoneuro-immunology]]></category>
		<category><![CDATA[Psychosis]]></category>
		<category><![CDATA[anti-inflammatory therapy]]></category>
		<category><![CDATA[immune system]]></category>
		<category><![CDATA[infection]]></category>
		<category><![CDATA[psychoneuroimmunology]]></category>
		<category><![CDATA[schizophrenia]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1066</guid>
		<description><![CDATA[Schizophrenia genes, epigenetics and psychoneuroimmunology therapeutics: all make sense now? J Psychopharmacol. 2011 Jun;25(6):713-4 M&#252;ller N, Dursun SM Abstract Genetics, epigenetics, infection as an environmental factor, functional findings for the immune system, and a therapeutic approach with anti-inflammatory therapy provide evidence for a pivotal role of the immune system in schizophrenia. This field, therefore, should [...]]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/09/05/schizophrenia-and-anti-inflammatory-therapy/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Seizures cause inflammation which sustains seizure recurrence and causes blood-brain barrier damage.</title>
		<link>http://www.definitivemind.com/2012/09/04/seizure-induced-brain-borne-inflammation-sustains-seizure-recurrence-and-blood-brain-barrier-damage/</link>
		<comments>http://www.definitivemind.com/2012/09/04/seizure-induced-brain-borne-inflammation-sustains-seizure-recurrence-and-blood-brain-barrier-damage/#comments</comments>
		<pubDate>Tue, 04 Sep 2012 20:20:30 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Cytokines]]></category>
		<category><![CDATA[Immunology]]></category>
		<category><![CDATA[Neurobiology]]></category>
		<category><![CDATA[Neurology]]></category>
		<category><![CDATA[Psychoneuro-immunology]]></category>
		<category><![CDATA[blood-brain barrier]]></category>
		<category><![CDATA[cytokines]]></category>
		<category><![CDATA[epilepsy]]></category>
		<category><![CDATA[IL-1β]]></category>
		<category><![CDATA[inflammation]]></category>
		<category><![CDATA[seizure]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1060</guid>
		<description><![CDATA[Seizure-induced brain-borne inflammation sustains seizure recurrence and blood-brain barrier damage Ann Neurol. 2012 Jul;72(1):82-90 Librizzi L, No&#232; F, Vezzani A, de Curtis M, Ravizza T Abstract OBJECTIVE: Epilepsy is a common neurological disorder characterized by recurrent seizures often unresponsive to pharmacological treatment. Brain inflammation is considered a crucial etiopathogenetic mechanism of epilepsy that could be [...]]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/09/04/seizure-induced-brain-borne-inflammation-sustains-seizure-recurrence-and-blood-brain-barrier-damage/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Psychoneuroimmunologic Factors In Inflammatory Bowel Disease</title>
		<link>http://www.definitivemind.com/2012/09/04/psychoneuroimmunologic-factors-in-inflammatory-bowel-disease/</link>
		<comments>http://www.definitivemind.com/2012/09/04/psychoneuroimmunologic-factors-in-inflammatory-bowel-disease/#comments</comments>
		<pubDate>Tue, 04 Sep 2012 08:32:19 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Inflammation]]></category>
		<category><![CDATA[Irritable Bowel Syndrome]]></category>
		<category><![CDATA[Psychoneuro-immunology]]></category>
		<category><![CDATA[cytokines]]></category>
		<category><![CDATA[HPA Axis]]></category>
		<category><![CDATA[inflammatory bowel disease]]></category>
		<category><![CDATA[Mast Cells]]></category>
		<category><![CDATA[Substance P]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1057</guid>
		<description><![CDATA[Psychoneuroimmunologic factors in inflammatory bowel disease Inflamm Bowel Dis. 2011 Mar;17(3):849-57 Authors: Mackner LM, Clough-Paabo E, Pajer K, Lourie A, Crandall WV Abstract BACKGROUND: Bidirectional relationships between the immune system, nervous system, and psychological processes likely exist in inflammatory bowel disease (IBD) because stress can affect IBD, and IBD is associated with an increased risk [...]]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/09/04/psychoneuroimmunologic-factors-in-inflammatory-bowel-disease/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Berries and flavonoids reduce cognitive decline.</title>
		<link>http://www.definitivemind.com/2012/09/03/ferries-and-flavonoids-reduce-cognitive-decline/</link>
		<comments>http://www.definitivemind.com/2012/09/03/ferries-and-flavonoids-reduce-cognitive-decline/#comments</comments>
		<pubDate>Mon, 03 Sep 2012 10:22:26 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Cognitive Disorders and Dementia]]></category>
		<category><![CDATA[Nutrition]]></category>
		<category><![CDATA[berries]]></category>
		<category><![CDATA[dementia]]></category>
		<category><![CDATA[flavonoids]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1050</guid>
		<description><![CDATA[Dietary intakes of berries and flavonoids in relation to cognitive decline Ann Neurol. 2012 Jul;72(1):135-43 Authors: Devore EE, Kang JH, Breteler MM, Grodstein F Abstract OBJECTIVE: Berries are high in flavonoids, especially anthocyanidins, and improve cognition in experimental studies. We prospectively evaluated whether greater long-term intakes of berries and flavonoids are associated with slower rates [...]]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/09/03/ferries-and-flavonoids-reduce-cognitive-decline/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Older Men Who Use Computers Have Lower Risk of Dementia</title>
		<link>http://www.definitivemind.com/2012/09/02/older-men-who-use-computers-have-lower-risk-of-dementia/</link>
		<comments>http://www.definitivemind.com/2012/09/02/older-men-who-use-computers-have-lower-risk-of-dementia/#comments</comments>
		<pubDate>Mon, 03 Sep 2012 07:18:00 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Cognitive Disorders and Dementia]]></category>
		<category><![CDATA[apoptosis]]></category>
		<category><![CDATA[computer use]]></category>
		<category><![CDATA[dementia]]></category>
		<category><![CDATA[education]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1047</guid>
		<description><![CDATA[Older men who use computers have lower risk of dementia. PLoS One. 2012;7(8):e44239. Epub 2012 Aug 28. Almeida OP, Yeap BB, Alfonso H, Hankey GJ, Flicker L, Norman PE. OBJECTIVE:To determine if older men who use computers have lower risk of developing dementia. METHODS:Cohort study of 5506 community-dwelling men aged 69 to 87 years followed [...]]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/09/02/older-men-who-use-computers-have-lower-risk-of-dementia/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>A comparison of psychiatry and internal medicine</title>
		<link>http://www.definitivemind.com/2012/09/02/a-comparison-of-psychiatry-and-internal-medicine/</link>
		<comments>http://www.definitivemind.com/2012/09/02/a-comparison-of-psychiatry-and-internal-medicine/#comments</comments>
		<pubDate>Sun, 02 Sep 2012 19:29:14 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[FEATURED]]></category>
		<category><![CDATA[General Medicine]]></category>
		<category><![CDATA[Psychiatry]]></category>
		<category><![CDATA[biological psychiatry]]></category>
		<category><![CDATA[featured]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1042</guid>
		<description><![CDATA[A comparison of psychiatry and internal medicine: a bibliometric study Acad Psychiatry. 2012 Mar 1;36(2):129-32 Stone K, Whitham EA, Ghaemi SN Abstract OBJECTIVE: Psychiatric education needs to expose students to a broad range of topics. One resource for psychiatric education, both during initial training and in later continuing medical education, is the scientific literature, as [...]]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/09/02/a-comparison-of-psychiatry-and-internal-medicine/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Reduced GABA Concentration in Attention-Deficit/Hyperactivity DisorderReduced GABA Concentration in ADHD.</title>
		<link>http://www.definitivemind.com/2012/09/02/reduced-gaba-concentration-in-attention-deficithyperactivity-disorderreduced-gaba-concentration-in-adhd/</link>
		<comments>http://www.definitivemind.com/2012/09/02/reduced-gaba-concentration-in-attention-deficithyperactivity-disorderreduced-gaba-concentration-in-adhd/#comments</comments>
		<pubDate>Sun, 02 Sep 2012 19:06:33 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Attention Deficit / Hyperactivity Disorder]]></category>
		<category><![CDATA[Neurobiology]]></category>
		<category><![CDATA[Neurotransmitters]]></category>
		<category><![CDATA[Psychiatry]]></category>
		<category><![CDATA[ADHD]]></category>
		<category><![CDATA[GABA]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1039</guid>
		<description><![CDATA[Reduced GABA Concentration in Attention-Deficit/Hyperactivity DisorderReduced GABA Concentration in ADHD Arch Gen Psychiatry. 2012 Jul 1;69(7):750-3 Authors: Edden RA, Crocetti D, Zhu H, Gilbert DL, Mostofsky SH Abstract CONTEXT Attention-deficit/hyperactivity disorder (ADHD) is a developmental disorder characterized by a deficit in behavioral inhibition. Recent evidence also suggests a deficit in cortical inhibition via the GABA [...]]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/09/02/reduced-gaba-concentration-in-attention-deficithyperactivity-disorderreduced-gaba-concentration-in-adhd/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Losartan Reduces Fibrosis and Improves Muscle Strength in Muscular Dystrophy Model</title>
		<link>http://www.definitivemind.com/2012/09/02/losartan-reduces-fibrosis-and-improves-muscle-strength-in-muscular-dystrophy-model/</link>
		<comments>http://www.definitivemind.com/2012/09/02/losartan-reduces-fibrosis-and-improves-muscle-strength-in-muscular-dystrophy-model/#comments</comments>
		<pubDate>Sun, 02 Sep 2012 18:48:25 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[General Medicine]]></category>
		<category><![CDATA[Medications]]></category>
		<category><![CDATA[Neurology]]></category>
		<category><![CDATA[ARBs]]></category>
		<category><![CDATA[losartan]]></category>
		<category><![CDATA[muscular dystrophy]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1036</guid>
		<description><![CDATA[Losartan, a therapeutic candidate in congenital muscular dystrophy: studies in the dy(2J) /dy(2J) mouse Ann Neurol. 2012 May;71(5):699-708 Elbaz M, Yanay N, Aga-Mizrachi S, Brunschwig Z, Kassis I, Ettinger K, Barak V, Nevo Y Abstract OBJECTIVE: Laminin&#945;2-deficient congenital muscular dystrophy type 1A (MDC1A) is a cureless disease associated with severe disability and shortened lifespan. Previous [...]]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/09/02/losartan-reduces-fibrosis-and-improves-muscle-strength-in-muscular-dystrophy-model/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Vitamin D Reduces Multiple Sclerosis Lesions</title>
		<link>http://www.definitivemind.com/2012/09/02/vitamin-d-reduces-multiple-sclerosis-lesions/</link>
		<comments>http://www.definitivemind.com/2012/09/02/vitamin-d-reduces-multiple-sclerosis-lesions/#comments</comments>
		<pubDate>Sun, 02 Sep 2012 18:35:39 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Neurology]]></category>
		<category><![CDATA[Nutrition]]></category>
		<category><![CDATA[Vitamins, Minerals and Other Nutrients]]></category>
		<category><![CDATA[multiple sclerosis]]></category>
		<category><![CDATA[vitamin D]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1033</guid>
		<description><![CDATA[Vitamin D status predicts new brain magnetic resonance imaging activity in multiple sclerosis Ann Neurol. 2012 Aug;72(2):234-40 Mowry EM, Waubant E, McCulloch CE, Okuda DT, Evangelista AA, Lincoln RR, Gourraud PA, Brenneman D, Owen MC, Qualley P, Bucci M, Hauser SL, Pelletier D Abstract OBJECTIVE: We sought to determine whether vitamin D status is associated [...]]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/09/02/vitamin-d-reduces-multiple-sclerosis-lesions/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Inflammatory Cytokine Cause Cognitive Impairment, Depression, And Sleep Disturbance And Other Non-Motor Symptoms Of Parkinsons Disease</title>
		<link>http://www.definitivemind.com/2012/09/02/inflammatory-cytokine-cause-cognitive-impairment-depression-and-sleep-disturbance-and-other-non-motor-symptoms-of-parkinsons-disease/</link>
		<comments>http://www.definitivemind.com/2012/09/02/inflammatory-cytokine-cause-cognitive-impairment-depression-and-sleep-disturbance-and-other-non-motor-symptoms-of-parkinsons-disease/#comments</comments>
		<pubDate>Sun, 02 Sep 2012 18:00:33 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Neurobiology]]></category>
		<category><![CDATA[Neurology]]></category>
		<category><![CDATA[Psychoneuro-immunology]]></category>
		<category><![CDATA[cytokines]]></category>
		<category><![CDATA[depression]]></category>
		<category><![CDATA[parkinson's disease]]></category>
		<category><![CDATA[tumor necrosis factor]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1030</guid>
		<description><![CDATA[The role of inflammatory cytokines in cognition and other non-motor symptoms of Parkinson&#8217;s disease. Psychosomatics. 2010 Nov-Dec;51(6):474-9. Menza M, Dobkin RD, Marin H, Mark MH, Gara M, Bienfait K, Dicke A, Kusnekov A. Abstract BACKGROUND:Parkinson&#8217;s disease (PD) affects patients&#8217; lives with more than just physical impairment. Many of the non-motor aspects of PD, such as [...]]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/09/02/inflammatory-cytokine-cause-cognitive-impairment-depression-and-sleep-disturbance-and-other-non-motor-symptoms-of-parkinsons-disease/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Viagra Reduces Insulin Resistance in Endothelial Cells</title>
		<link>http://www.definitivemind.com/2012/09/01/viagra-reduces-insulin-resistance-in-endothelial-cells/</link>
		<comments>http://www.definitivemind.com/2012/09/01/viagra-reduces-insulin-resistance-in-endothelial-cells/#comments</comments>
		<pubDate>Sat, 01 Sep 2012 23:19:48 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Cardiovascular]]></category>
		<category><![CDATA[Endocrinology]]></category>
		<category><![CDATA[Medications]]></category>
		<category><![CDATA[diabetes]]></category>
		<category><![CDATA[insulin resistance]]></category>
		<category><![CDATA[sildenafil]]></category>
		<category><![CDATA[viagra]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1024</guid>
		<description><![CDATA[Sildenafil reduces insulin-resistance in human endothelial cells PLoS One. 2011 Jan 28;6(1):e14542.Mammi C, Pastore D, Lombardo MF, Ferrelli F, Caprio M, Consoli C, Tesauro M, Gatta L, Fini M, Federici M, Sbraccia P, Donadel G, Bellia A, Rosano GM, Fabbri A, Lauro D. Abstract BACKGROUND:The efficacy of Phosphodiesterase 5 (PDE5) inhibitors to re-establish endothelial function [...]]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/09/01/viagra-reduces-insulin-resistance-in-endothelial-cells/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Yogic Meditation Reduces Inflammation By Reducing NF-&#954;B and Increasing IRF -related Gene Transcription of Pro-inflammatory Cytokines</title>
		<link>http://www.definitivemind.com/2012/09/01/yogic-meditation-reduces-inflammation-by-reducing-nf-b-and-increasing-irf-related-gene-transcription-of-pro-inflammatory-cytokines/</link>
		<comments>http://www.definitivemind.com/2012/09/01/yogic-meditation-reduces-inflammation-by-reducing-nf-b-and-increasing-irf-related-gene-transcription-of-pro-inflammatory-cytokines/#comments</comments>
		<pubDate>Sat, 01 Sep 2012 19:36:21 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Neurobiology]]></category>
		<category><![CDATA[Psychology]]></category>
		<category><![CDATA[Psychoneuro-immunology]]></category>
		<category><![CDATA[Psychosocial]]></category>
		<category><![CDATA[inflammation]]></category>
		<category><![CDATA[interferone]]></category>
		<category><![CDATA[meditation]]></category>
		<category><![CDATA[NF-κB]]></category>
		<category><![CDATA[yoga]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1021</guid>
		<description><![CDATA[Yogic meditation reverses NF-&#954;B and IRF-related transcriptome dynamics in leukocytes of family dementia caregivers in a randomized controlled trial Psychoneuroendocrinology. 2012 Jul 13; Black DS, Cole SW, Irwin MR, Breen E, St Cyr NM, Nazarian N, Khalsa DS, Lavretsky H Abstract BACKGROUND: Although yoga and meditation have been used for stress reduction with reported improvement [...]]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/09/01/yogic-meditation-reduces-inflammation-by-reducing-nf-b-and-increasing-irf-related-gene-transcription-of-pro-inflammatory-cytokines/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Brief Wakeful Resting Boosts Memory Consolidation and Retention</title>
		<link>http://www.definitivemind.com/2012/09/01/brief-wakeful-resting-boosts-memory-consolidation-and-retension/</link>
		<comments>http://www.definitivemind.com/2012/09/01/brief-wakeful-resting-boosts-memory-consolidation-and-retension/#comments</comments>
		<pubDate>Sat, 01 Sep 2012 18:53:13 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Mental Health]]></category>
		<category><![CDATA[Neurobiology]]></category>
		<category><![CDATA[Psychology]]></category>
		<category><![CDATA[learning]]></category>
		<category><![CDATA[memory]]></category>
		<category><![CDATA[sleep]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1018</guid>
		<description><![CDATA[Brief Wakeful Resting Boosts New Memories Over the Long Term Psychol Sci. 2012 Jul 24; Dewar M, Alber J, Butler C, Cowan N, Della Sala S Abstract A brief wakeful rest after new verbal learning enhances memory for several minutes. In the research reported here, we explored the possibility of extending this rest-induced memory enhancement [...]]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/09/01/brief-wakeful-resting-boosts-memory-consolidation-and-retension/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Valproic Acid helps T-Cells Kill Cancer Cells</title>
		<link>http://www.definitivemind.com/2012/08/31/valproic-acid-helps-t-cells-kill-cancer-cells/</link>
		<comments>http://www.definitivemind.com/2012/08/31/valproic-acid-helps-t-cells-kill-cancer-cells/#comments</comments>
		<pubDate>Sat, 01 Sep 2012 07:52:23 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Cancer]]></category>
		<category><![CDATA[Medications]]></category>
		<category><![CDATA[cancer]]></category>
		<category><![CDATA[depakote]]></category>
		<category><![CDATA[t-cells]]></category>
		<category><![CDATA[valproic acid]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1015</guid>
		<description><![CDATA[The antitumour effect of {gamma}{delta} T-cells is enhanced by valproic acid-induced up-regulation of NKG2D ligands Anticancer Res. 2010 Nov;30(11):4509-13 Suzuki T, Terao S, Acharya B, Naoe M, Yamamoto S, Okamura H, Gotoh A Abstract BACKGROUND: The aim of this study wsa to evaluate the additive effect of valproic acid (VPA) to &#947;&#948; T-cell cytotoxicity against [...]]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/08/31/valproic-acid-helps-t-cells-kill-cancer-cells/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Probiotic Bacteria Protect Against Viral Illness</title>
		<link>http://www.definitivemind.com/2012/08/31/probiotic-bacteria-protect-against-viral-illness/</link>
		<comments>http://www.definitivemind.com/2012/08/31/probiotic-bacteria-protect-against-viral-illness/#comments</comments>
		<pubDate>Sat, 01 Sep 2012 02:55:37 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Complementary Medicine]]></category>
		<category><![CDATA[Gastroenterology]]></category>
		<category><![CDATA[Immunology]]></category>
		<category><![CDATA[Inflammation]]></category>
		<category><![CDATA[Nutrition]]></category>
		<category><![CDATA[Vitamins, Minerals and Other Nutrients]]></category>
		<category><![CDATA[AIDS]]></category>
		<category><![CDATA[probiotics]]></category>
		<category><![CDATA[Virus]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1012</guid>
		<description><![CDATA[Effect of probiotic bacteria on microbial host defense, growth, and immune function in human immunodeficiency virus type-1 infection. Nutrients. 2011 Dec;3(12):1042-70. Epub 2011 Dec 19. Cunningham-Rundles S, Ahrn&#233; S, Johann-Liang R, Abuav R, Dunn-Navarra AM, Grassey C, Bengmark S, Cervia JS. Abstract The hypothesis that probiotic administration protects the gut surface and could delay progression [...]]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/08/31/probiotic-bacteria-protect-against-viral-illness/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Would lowering the diagnostic criteria for bipolar disorder do more harm than good? Yes</title>
		<link>http://www.definitivemind.com/2012/08/31/would-lowering-the-diagnostic-criteria-for-bipolar-disorder-do-more-harm-than-good-yes/</link>
		<comments>http://www.definitivemind.com/2012/08/31/would-lowering-the-diagnostic-criteria-for-bipolar-disorder-do-more-harm-than-good-yes/#comments</comments>
		<pubDate>Fri, 31 Aug 2012 18:43:12 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Bipolar Disorder]]></category>
		<category><![CDATA[bipolar disorder]]></category>
		<category><![CDATA[DSM-IV]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1007</guid>
		<description><![CDATA[Would broadening the diagnostic criteria for bipolar disorder do more harm than good? Implications from longitudinal studies of subthreshold conditions. J Clin Psychiatry. 2012 Apr;73(4):437-43 Zimmerman M Abstract BACKGROUND: The Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV), is a categorical system that provides descriptive diagnostic criteria for psychiatric syndromes. These syndrome descriptions [...]]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/08/31/would-lowering-the-diagnostic-criteria-for-bipolar-disorder-do-more-harm-than-good-yes/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>The renin-angiotensin pathway in PTSD: ACE inhibitors and ARBs are associated with fewer PTSD symptoms.</title>
		<link>http://www.definitivemind.com/2012/08/29/the-renin-angiotensin-pathway-in-ptsd-ace-inhibitors-and-arbs-are-associated-with-fewer-ptsd-symptoms/</link>
		<comments>http://www.definitivemind.com/2012/08/29/the-renin-angiotensin-pathway-in-ptsd-ace-inhibitors-and-arbs-are-associated-with-fewer-ptsd-symptoms/#comments</comments>
		<pubDate>Wed, 29 Aug 2012 20:44:39 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Anxiety Disorders]]></category>
		<category><![CDATA[Cardiovascular]]></category>
		<category><![CDATA[General Medicine]]></category>
		<category><![CDATA[Medications]]></category>
		<category><![CDATA[Neurobiology]]></category>
		<category><![CDATA[PTSD]]></category>
		<category><![CDATA[ACE inhibitors]]></category>
		<category><![CDATA[aldosterone]]></category>
		<category><![CDATA[angiotensin]]></category>
		<category><![CDATA[ARBs]]></category>
		<category><![CDATA[renin]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=1001</guid>
		<description><![CDATA[The renin-angiotensin pathway in posttraumatic stress disorder: angiotensin-converting enzyme inhibitors and angiotensin receptor blockers are associated with fewer traumatic stress symptoms. J Clin Psychiatry. 2012 Jun;73(6):849-55 Khoury NM, Marvar PJ, Gillespie CF, Wingo A, Schwartz A, Bradley B, Kramer M, Ressler KJ Abstract OBJECTIVE:&#160;Posttraumatic stress disorder (PTSD) is a debilitating stress-related illness associated with trauma [...]]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/08/29/the-renin-angiotensin-pathway-in-ptsd-ace-inhibitors-and-arbs-are-associated-with-fewer-ptsd-symptoms/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Benzodiazepines Help Kill Cancer Cells</title>
		<link>http://www.definitivemind.com/2012/08/28/benzodiazepines-help-kill-cancer-cells/</link>
		<comments>http://www.definitivemind.com/2012/08/28/benzodiazepines-help-kill-cancer-cells/#comments</comments>
		<pubDate>Wed, 29 Aug 2012 07:06:26 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Biology]]></category>
		<category><![CDATA[Cancer]]></category>
		<category><![CDATA[Medications]]></category>
		<category><![CDATA[apoptosis]]></category>
		<category><![CDATA[benzodiazepines]]></category>
		<category><![CDATA[cancer]]></category>
		<category><![CDATA[diazepam]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=996</guid>
		<description><![CDATA[Peripheral benzodiazepine receptor ligands reverse apoptosis resistance of cancer cells in vitro and in vivo Cancer Res. 2002 Mar 1;62(5):1388-93 Decaudin D, Castedo M, Nemati F, Beurdeley-Thomas A, De Pinieux G, Caron A, Pouillart P, Wijdenes J, Rouillard D, Kroemer G, Poupon MF Abstract The mitochondrial peripheral benzodiazepine receptor (mPBR) is involved in a functional [...]]]></description>
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		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Vitamin C Reduces Benzodiazepine-induced Immunosuppression and Immune Cell Apoptosis</title>
		<link>http://www.definitivemind.com/2012/08/28/vitamin-c-reduces-benzodiazepine-induced-immunosuppression/</link>
		<comments>http://www.definitivemind.com/2012/08/28/vitamin-c-reduces-benzodiazepine-induced-immunosuppression/#comments</comments>
		<pubDate>Wed, 29 Aug 2012 06:59:58 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Immunology]]></category>
		<category><![CDATA[Medications]]></category>
		<category><![CDATA[Vitamins, Minerals and Other Nutrients]]></category>
		<category><![CDATA[apoptosis]]></category>
		<category><![CDATA[benzodiazepine]]></category>
		<category><![CDATA[immunology]]></category>
		<category><![CDATA[immunosuppression]]></category>
		<category><![CDATA[lymphocytes]]></category>
		<category><![CDATA[Nutrition]]></category>
		<category><![CDATA[vitamin c]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=993</guid>
		<description><![CDATA[Protective role of vitamin C in diazepam-induced apoptosis in rat thymocytes Bratisl Lek Listy. 2012;113(6):350-3 Authors: Pavlovic V, Pavlovic D, Kamenov B, Sarac M, Peric Z, Velojic M Abstract Diazepam, a peripheral-type benzodiazepine receptor ligand, is widely used as a therapeutic agent. On the other hand, peripheral-type benzodiazepines have been shown to induce apoptosis in [...]]]></description>
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		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Quetiapine enhances oligodendrocyte regeneration and myelin repair</title>
		<link>http://www.definitivemind.com/2012/08/28/quetiapine-enhances-oligodendrocyte-regeneration-and-myelin-repair/</link>
		<comments>http://www.definitivemind.com/2012/08/28/quetiapine-enhances-oligodendrocyte-regeneration-and-myelin-repair/#comments</comments>
		<pubDate>Wed, 29 Aug 2012 06:07:52 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Medications]]></category>
		<category><![CDATA[Neurobiology]]></category>
		<category><![CDATA[Pharmacology]]></category>
		<category><![CDATA[Psychosis]]></category>
		<category><![CDATA[glia]]></category>
		<category><![CDATA[myelin]]></category>
		<category><![CDATA[oligodendrocyte]]></category>
		<category><![CDATA[quetiapine]]></category>
		<category><![CDATA[schizophrenia]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=988</guid>
		<description><![CDATA[Quetiapine enhances oligodendrocyte regeneration and myelin repair after cuprizone-induced demyelination Schizophr Res. 2012 Jun;138(1):8-17 Zhang Y, Zhang H, Wang L, Jiang W, Xu H, Xiao L, Bi X, Wang J, Zhu S, Zhang R, He J, Tan Q, Zhang D, Kong J, Li XM Abstract Myelin and oligodendrocyte dysfunctions have been consistently found in patients [...]]]></description>
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		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Infection in the body increases microglia activation, increases the number of inflammatory CNS macrophages, and promotes social withdrawal</title>
		<link>http://www.definitivemind.com/2012/08/28/bacterial-infection-increases-microglia-activation-increases-the-number-of-inflammatory-cns-macrophages-and-promotes-social-withdrawal/</link>
		<comments>http://www.definitivemind.com/2012/08/28/bacterial-infection-increases-microglia-activation-increases-the-number-of-inflammatory-cns-macrophages-and-promotes-social-withdrawal/#comments</comments>
		<pubDate>Tue, 28 Aug 2012 08:55:46 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Anxiety Disorders]]></category>
		<category><![CDATA[Cytokine]]></category>
		<category><![CDATA[Depression]]></category>
		<category><![CDATA[Immunology]]></category>
		<category><![CDATA[Inflammation]]></category>
		<category><![CDATA[Psychoneuro-immunology]]></category>
		<category><![CDATA[infection]]></category>
		<category><![CDATA[macrophage]]></category>
		<category><![CDATA[microglia]]></category>
		<category><![CDATA[social withdrawal]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=983</guid>
		<description><![CDATA[Peripheral innate immune challenge exaggerated microglia activation, increased the number of inflammatory CNS macrophages, and prolonged social withdrawal in socially defeated mice. Psychoneuroendocrinology. 2012 Mar 1; Authors: Wohleb ES, Fenn AM, Pacenta AM, Powell ND, Sheridan JF, Godbout JP Abstract Repeated social defeat (RSD) activates neuroendocrine pathways that have a significant influence on immunity and [...]]]></description>
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		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Immune System Pro-inflammatory Actions Impair Neuroplasticity During Depression</title>
		<link>http://www.definitivemind.com/2012/08/28/immune-system-pro-inflammatory-actions-impair-neuroplasticity-during-depression/</link>
		<comments>http://www.definitivemind.com/2012/08/28/immune-system-pro-inflammatory-actions-impair-neuroplasticity-during-depression/#comments</comments>
		<pubDate>Tue, 28 Aug 2012 08:45:18 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Cytokine]]></category>
		<category><![CDATA[Depression]]></category>
		<category><![CDATA[Immunology]]></category>
		<category><![CDATA[Inflammation]]></category>
		<category><![CDATA[Mind-Body Medicine]]></category>
		<category><![CDATA[Neuroplasticity]]></category>
		<category><![CDATA[Psychoneuro-immunology]]></category>
		<category><![CDATA[cytokines]]></category>
		<category><![CDATA[depression]]></category>
		<category><![CDATA[immune system]]></category>
		<category><![CDATA[neuroplasticity]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=980</guid>
		<description><![CDATA[Neuroplastic changes in depression: A role for the immune system Psychoneuroendocrinology. 2012 Apr 21; Authors: Eyre H, Baune BT Abstract Accumulating evidence suggests that there is a rich cross-talk between the neuroimmune system and neuroplasticity mechanisms under both physiological conditions and pathophysiological conditions in depression. Anti-neuroplastic changes which occur in depression include a decrease in [...]]]></description>
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		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Celebrex (Celecoxib) and GABA Reduce while Social Stresses Increase Progression of Pancreatic Cancer</title>
		<link>http://www.definitivemind.com/2012/08/27/celecoxib-and-gaba-reduce-while-social-stress-increases-progression-of-pancreatic-cancer/</link>
		<comments>http://www.definitivemind.com/2012/08/27/celecoxib-and-gaba-reduce-while-social-stress-increases-progression-of-pancreatic-cancer/#comments</comments>
		<pubDate>Tue, 28 Aug 2012 07:07:52 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Anxiety Disorders]]></category>
		<category><![CDATA[Biology]]></category>
		<category><![CDATA[Complementary Medicine]]></category>
		<category><![CDATA[Gastroenterology]]></category>
		<category><![CDATA[Immunology]]></category>
		<category><![CDATA[Medications]]></category>
		<category><![CDATA[Mental Health]]></category>
		<category><![CDATA[Mind-Body Medicine]]></category>
		<category><![CDATA[Pharmacology]]></category>
		<category><![CDATA[Psychosocial]]></category>
		<category><![CDATA[celebrex]]></category>
		<category><![CDATA[celecoxib]]></category>
		<category><![CDATA[GABA]]></category>
		<category><![CDATA[pancreatic cancer]]></category>
		<category><![CDATA[stress]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=924</guid>
		<description><![CDATA[Celecoxib and GABA Cooperatively Prevent the Progression of Pancreatic Cancer In Vitro and in Xenograft Models of Stress-Free and Stress-Exposed Mice PLoS One. 2012;7(8):e43376. Epub 2012 Aug 16. Al-Wadei HA, Al-Wadei MH, Ullah MF, Schuller HM. Abstract Pancreatic ductal adenocarcinoma (PDAC) has a poor prognosis and is associated with high levels of psychological distress. We [...]]]></description>
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		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Antidepressant Combination for Major Depression: Flaws in Evidenced-Based Medicine</title>
		<link>http://www.definitivemind.com/2012/08/27/antidepressant-combination-for-major-depression-flaws-in-evidenced-based-medicine/</link>
		<comments>http://www.definitivemind.com/2012/08/27/antidepressant-combination-for-major-depression-flaws-in-evidenced-based-medicine/#comments</comments>
		<pubDate>Mon, 27 Aug 2012 19:14:44 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Depression]]></category>
		<category><![CDATA[Medications]]></category>
		<category><![CDATA[Psychiatry]]></category>
		<category><![CDATA[Study Design Limitations]]></category>
		<category><![CDATA[antidepressants]]></category>
		<category><![CDATA[depression]]></category>
		<category><![CDATA[evidence-based]]></category>
		<category><![CDATA[study design]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=905</guid>
		<description><![CDATA[Antidepressant combination for major depression in incomplete responders-a systematic review. J Affect Disord. 2012 Jul 24; Authors: Lopes Rocha F, Fuzikawa C, Riera R, Ramos MG, Hara C Abstract BACKGROUND: Antidepressant combination has been suggested as a strategy to increase treatment efficacy. The objective of this study was to perform a systematic review and meta-analysis [...]]]></description>
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		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Obesity Increases the Risk for Depression Particularly if Not Metabolically Healthy</title>
		<link>http://www.definitivemind.com/2012/08/26/obesity-increases-the-risk-for-depression-particularly-if-not-metabolically-healthy/</link>
		<comments>http://www.definitivemind.com/2012/08/26/obesity-increases-the-risk-for-depression-particularly-if-not-metabolically-healthy/#comments</comments>
		<pubDate>Mon, 27 Aug 2012 07:53:45 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Depression]]></category>
		<category><![CDATA[Metabolism]]></category>
		<category><![CDATA[Obesity]]></category>
		<category><![CDATA[depression]]></category>
		<category><![CDATA[metabolic]]></category>
		<category><![CDATA[obesity]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=902</guid>
		<description><![CDATA[Risk of future depression in people who are obese but metabolically healthy: the English longitudinal study of ageing Molecular Psychiatry 17, 940 (September 2012). doi:10.1038/mp.2012.30 M Hamer, G D Batty &#38; M Kivimaki Abstract There is some evidence to suggest that obesity is a risk factor for the development of depression, although this is not [...]]]></description>
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		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Amygdala is smaller in bipolar disorder depressed patients</title>
		<link>http://www.definitivemind.com/2012/08/24/amygdala-is-smaller-in-bipolar-disorder-depressed-patients/</link>
		<comments>http://www.definitivemind.com/2012/08/24/amygdala-is-smaller-in-bipolar-disorder-depressed-patients/#comments</comments>
		<pubDate>Fri, 24 Aug 2012 21:16:10 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Bipolar Disorder]]></category>
		<category><![CDATA[Depression]]></category>
		<category><![CDATA[Neurobiology]]></category>
		<category><![CDATA[Study Design Limitations]]></category>
		<category><![CDATA[amygdala]]></category>
		<category><![CDATA[bipolar disorder]]></category>
		<category><![CDATA[depression]]></category>
		<category><![CDATA[MRI]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=892</guid>
		<description><![CDATA[Mood-state effects on amygdala volume in bipolar disorder J Affect Disord. 2012 Aug;139(3):298-301 Authors: Foland-Ross LC, Brooks JO, Mintz J, Bartzokis G, Townsend J, Thompson PM, Altshuler LL Abstract BACKGROUND: Prior structural neuroimaging studies of the amygdala in patients with bipolar disorder have reported higher or lower volumes, or no difference relative to healthy controls. [...]]]></description>
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		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>This is what thought looks like &#8211; and it isn&#8217;t random</title>
		<link>http://www.definitivemind.com/2012/08/24/this-is-what-thought-looks-like-and-it-isnt-random/</link>
		<comments>http://www.definitivemind.com/2012/08/24/this-is-what-thought-looks-like-and-it-isnt-random/#comments</comments>
		<pubDate>Fri, 24 Aug 2012 18:38:37 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[FEATURED]]></category>
		<category><![CDATA[Neurobiology]]></category>
		<category><![CDATA[astrocyte]]></category>
		<category><![CDATA[calcium wave]]></category>
		<category><![CDATA[featured]]></category>
		<category><![CDATA[gap junction]]></category>
		<category><![CDATA[glia]]></category>
		<category><![CDATA[neurobiology]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=875</guid>
		<description><![CDATA[Astrocytes are seen signaling through gap junctions using calcium waves in this video from garlandscien.]]></description>
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		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Children with ADHD and Anger have a Mood Disorder Too</title>
		<link>http://www.definitivemind.com/2012/08/24/children-with-adhd-with-anger-have-a-mood-disorder-too/</link>
		<comments>http://www.definitivemind.com/2012/08/24/children-with-adhd-with-anger-have-a-mood-disorder-too/#comments</comments>
		<pubDate>Fri, 24 Aug 2012 18:16:28 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[FEATURED]]></category>
		<category><![CDATA[Hypertension]]></category>
		<category><![CDATA[Laboratory Science]]></category>
		<category><![CDATA[Metabolism]]></category>
		<category><![CDATA[Pharmacology]]></category>
		<category><![CDATA[Philosophy]]></category>
		<category><![CDATA[Psychiatry]]></category>
		<category><![CDATA[Psychoneuro-immunology]]></category>
		<category><![CDATA[RESOURCES]]></category>
		<category><![CDATA[STICKIES]]></category>
		<category><![CDATA[Study Design Limitations]]></category>
		<category><![CDATA[ADHD]]></category>
		<category><![CDATA[bipolar disorder]]></category>
		<category><![CDATA[featured]]></category>
		<category><![CDATA[study design]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=870</guid>
		<description><![CDATA[Pediatric bipolar disorder and ADHD: Family history comparison in the LAMS clinical sample J Affect Disord. 2012 Mar 30; Authors: Arnold LE, Mount K, Frazier T, Demeter C, Youngstrom EA, Fristad MA, Birmaher B, Horwitz S, Findling RL, Kowatch R, Axelson D Abstract &#160; BACKGROUND: Transgenerational association of bipolar spectrum disorder (BPSD) and attention deficit/hyperactivity [...]]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/08/24/children-with-adhd-with-anger-have-a-mood-disorder-too/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>The Problem of Meta-Analysis of Psychotherapy&#8217;s Effect on Suicidality</title>
		<link>http://www.definitivemind.com/2012/08/24/the-problem-of-meta-analysis-of-psychotherapys-effect-on-suicidality/</link>
		<comments>http://www.definitivemind.com/2012/08/24/the-problem-of-meta-analysis-of-psychotherapys-effect-on-suicidality/#comments</comments>
		<pubDate>Fri, 24 Aug 2012 17:36:50 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Consciousness]]></category>
		<category><![CDATA[Neurobiology]]></category>
		<category><![CDATA[Psychiatry]]></category>
		<category><![CDATA[Psychology]]></category>
		<category><![CDATA[Psychosocial]]></category>
		<category><![CDATA[Psychotherapy]]></category>
		<category><![CDATA[Study Design Limitations]]></category>
		<category><![CDATA[DBT]]></category>
		<category><![CDATA[dialectical behavioral therapy]]></category>
		<category><![CDATA[meta-analysis]]></category>
		<category><![CDATA[psychotherapy]]></category>
		<category><![CDATA[suicidaility]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=867</guid>
		<description><![CDATA[The effects of psychotherapy for adult depression on suicidality and hopelessness: A systematic review and meta-analysis J Affect Disord. 2012 Jul 23; Authors: Cuijpers P, de Beurs DP, van Spijker BA, Berking M, Andersson G, Kerkhof AJ Abstract BACKGROUND: Although treatment guidelines suggest that suicidal patients with depression should be treated for depression with psychotherapy, [...]]]></description>
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		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Celebrex is a Potent Antidepressant</title>
		<link>http://www.definitivemind.com/2012/08/23/celecoxib-celebrex-reduces-depression-by-reducing-interleukin-6/</link>
		<comments>http://www.definitivemind.com/2012/08/23/celecoxib-celebrex-reduces-depression-by-reducing-interleukin-6/#comments</comments>
		<pubDate>Fri, 24 Aug 2012 07:46:26 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Complementary Medicine]]></category>
		<category><![CDATA[Cytokines]]></category>
		<category><![CDATA[Eicosinoids]]></category>
		<category><![CDATA[FEATURED]]></category>
		<category><![CDATA[General Medicine]]></category>
		<category><![CDATA[Immunology]]></category>
		<category><![CDATA[Mental Health]]></category>
		<category><![CDATA[Mood Disorders]]></category>
		<category><![CDATA[Neuro-endocrinology]]></category>
		<category><![CDATA[Neurobiology]]></category>
		<category><![CDATA[Pathophysiology]]></category>
		<category><![CDATA[Pharmacology]]></category>
		<category><![CDATA[Psychiatry]]></category>
		<category><![CDATA[Psychology]]></category>
		<category><![CDATA[Psychoneuro-immunology]]></category>
		<category><![CDATA[Study Design Limitations]]></category>
		<category><![CDATA[celebrex]]></category>
		<category><![CDATA[celicoxib]]></category>
		<category><![CDATA[depression]]></category>
		<category><![CDATA[IL-6]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=854</guid>
		<description><![CDATA[Effect of celecoxib add-on treatment on symptoms and serum IL-6 concentrations in patients with major depressive disorder: Randomized double-blind placebo-controlled study J Affect Disord. 2012 Apr 18; Authors: Abbasi SH, Hosseini F, Modabbernia A, Ashrafi M, Akhondzadeh S Abstract BACKGROUND: It has been proposed that the mechanism of the antidepressant effect of celecoxib is linked [...]]]></description>
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		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Omega-3 Fatty Acids Improve Capacity to Adapt to Stress</title>
		<link>http://www.definitivemind.com/2012/08/23/omega-3-fatty-acids-improve-capacity-to-adapt-to-chronic-restraint-stress/</link>
		<comments>http://www.definitivemind.com/2012/08/23/omega-3-fatty-acids-improve-capacity-to-adapt-to-chronic-restraint-stress/#comments</comments>
		<pubDate>Fri, 24 Aug 2012 06:34:14 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Anxiety Disorders]]></category>
		<category><![CDATA[Depression]]></category>
		<category><![CDATA[Neuro-endocrinology]]></category>
		<category><![CDATA[Nutrition]]></category>
		<category><![CDATA[corticosterone]]></category>
		<category><![CDATA[fatty acids]]></category>
		<category><![CDATA[omega-3]]></category>
		<category><![CDATA[stress]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=849</guid>
		<description><![CDATA[Influence of Omega-3 Fatty Acid Status on the Way Rats Adapt to Chronic Restraint Stress PLoS One. 2012;7(7):e42142. Epub 2012 Jul 30. Hennebelle M, Balasse L, Latour A, Champeil-Potokar G, Denis S, Lavialle M, Gisquet-Verrier P, Denis I, Vancassel S. Abstract Omega-3 fatty acids are important for several neuronal and cognitive functions. Altered omega-3 fatty [...]]]></description>
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		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>CALCULATORS</title>
		<link>http://www.definitivemind.com/2012/08/22/calculators/</link>
		<comments>http://www.definitivemind.com/2012/08/22/calculators/#comments</comments>
		<pubDate>Wed, 22 Aug 2012 14:01:02 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[FEATURED]]></category>
		<category><![CDATA[STICKIES]]></category>
		<category><![CDATA[calculator]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=813</guid>
		<description><![CDATA[]]></description>
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		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>150 Minutes a Week of Weight Training plus Aerobic Exercise Reduces Risk of Diabetes</title>
		<link>http://www.definitivemind.com/2012/08/19/weight-training-and-aerobic-exercise-reduces-risk-of-diabetes/</link>
		<comments>http://www.definitivemind.com/2012/08/19/weight-training-and-aerobic-exercise-reduces-risk-of-diabetes/#comments</comments>
		<pubDate>Sun, 19 Aug 2012 08:50:08 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Endocrinology]]></category>
		<category><![CDATA[Exercise]]></category>
		<category><![CDATA[Neuro-endocrinology]]></category>
		<category><![CDATA[diabetes]]></category>
		<category><![CDATA[exercise]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=781</guid>
		<description><![CDATA[A Prospective Study of Weight Training and Risk of Type 2 Diabetes Mellitus in Men Arch Intern Med. 2012 Aug 6;:1-7 Authors: Gr&#248;ntved A, Rimm EB, Willett WC, Andersen LB, Hu FB Abstract BACKGROUND The role of weight training in the primary prevention of type 2 diabetes mellitus (T2DM) is largely unknown. METHODS To examine [...]]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/08/19/weight-training-and-aerobic-exercise-reduces-risk-of-diabetes/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Residual Memory Dysfunction In Major Depressive Disorder Means Incomplete Treatment</title>
		<link>http://www.definitivemind.com/2012/08/17/residual-memory-dysfunction-in-recurrent-major-depressive-disorder/</link>
		<comments>http://www.definitivemind.com/2012/08/17/residual-memory-dysfunction-in-recurrent-major-depressive-disorder/#comments</comments>
		<pubDate>Sat, 18 Aug 2012 07:54:15 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Cognitive Disorders and Dementia]]></category>
		<category><![CDATA[FEATURED]]></category>
		<category><![CDATA[Medications]]></category>
		<category><![CDATA[Psychiatry]]></category>
		<category><![CDATA[depression]]></category>
		<category><![CDATA[memory]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=737</guid>
		<description><![CDATA[Residual memory dysfunction in recurrent major depressive disorder-A longitudinal study from Juntendo University Mood Disorder Project J Affect Disord. 2012 Jul 23; Authors: Maeshima H, Baba H, Nakano Y, Satomura E, Namekawa Y, Takebayashi N, Suzuki T, Mimura M, Arai H Abstract BACKGROUND: Depression may increase the risk of developing Alzheimer&#8217;s disease. Large cohort studies [...]]]></description>
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		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Oxytocin Enhances Adaptive Response to Social Stress</title>
		<link>http://www.definitivemind.com/2012/08/17/oxytocin-enhances-adaptive-response-to-social-stress/</link>
		<comments>http://www.definitivemind.com/2012/08/17/oxytocin-enhances-adaptive-response-to-social-stress/#comments</comments>
		<pubDate>Sat, 18 Aug 2012 05:04:50 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Neuro-endocrinology]]></category>
		<category><![CDATA[Psychology]]></category>
		<category><![CDATA[oxytocin]]></category>
		<category><![CDATA[social]]></category>
		<category><![CDATA[stress]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=734</guid>
		<description><![CDATA[A heartfelt response: Oxytocin effects on response to social stress in men and women &#160; Biol Psychol. 2012 Apr;90(1):1-9 Authors: Kubzansky LD, Mendes WB, Appleton AA, Block J, Adler GK Abstract BACKGROUND: Animal research indicates that oxytocin is involved in social behavior, stress regulation, and positive physiologic adaptation. This study examines whether oxytocin enhances adaptive [...]]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/08/17/oxytocin-enhances-adaptive-response-to-social-stress/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Selenium and prostate cancer</title>
		<link>http://www.definitivemind.com/2012/08/17/selenium-and-prostate-cancer/</link>
		<comments>http://www.definitivemind.com/2012/08/17/selenium-and-prostate-cancer/#comments</comments>
		<pubDate>Sat, 18 Aug 2012 04:38:11 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Nutrition]]></category>
		<category><![CDATA[TOPICS]]></category>
		<category><![CDATA[cancer]]></category>
		<category><![CDATA[prostate]]></category>
		<category><![CDATA[selenium]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=731</guid>
		<description><![CDATA[Selenium and prostate cancer: systematic review and meta-analysis &#160; Am J Clin Nutr. 2012 Jul;96(1):111-22 Authors: Hurst R, Hooper L, Norat T, Lau R, Aune D, Greenwood DC, Vieira R, Collings R, Harvey LJ, Sterne JA, Beynon R, Savovic J, Fairweather-Tait SJ Abstract BACKGROUND: Prostate cancer is a growing public health problem. Several human studies [...]]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/08/17/selenium-and-prostate-cancer/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Maternal Gluten Sensitivity Raises Risk for Psychosis in Children</title>
		<link>http://www.definitivemind.com/2012/08/17/maternal-gluten-sensitivity-raises-risk-for-psychosis-in-children/</link>
		<comments>http://www.definitivemind.com/2012/08/17/maternal-gluten-sensitivity-raises-risk-for-psychosis-in-children/#comments</comments>
		<pubDate>Fri, 17 Aug 2012 20:20:38 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Mental Health]]></category>
		<category><![CDATA[Psychiatry]]></category>
		<category><![CDATA[Psychoneuro-immunology]]></category>
		<category><![CDATA[gluten]]></category>
		<category><![CDATA[psychosis]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=728</guid>
		<description><![CDATA[Maternal antibodies to dietary antigens and risk for nonaffective psychosis in offspring &#160; Am J Psychiatry. 2012 Jun;169(6):625-32 Authors: Karlsson H, Blomstr&#246;m &#197;, Wicks S, Yang S, Yolken RH, Dalman C Abstract OBJECTIVE:The authors analyzed archival dried blood spots obtained from newborns to assess whether levels of immunoglobulin G (IgG) directed at dietary antigens were [...]]]></description>
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		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Bereavement Induces Systemic Inflammation</title>
		<link>http://www.definitivemind.com/2012/08/16/bereavement-induced-systemic-inflammation-in-susceptible-persons/</link>
		<comments>http://www.definitivemind.com/2012/08/16/bereavement-induced-systemic-inflammation-in-susceptible-persons/#comments</comments>
		<pubDate>Fri, 17 Aug 2012 00:50:20 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[FEATURED]]></category>
		<category><![CDATA[Psychiatry]]></category>
		<category><![CDATA[Psychoneuro-immunology]]></category>
		<category><![CDATA[bereavement]]></category>
		<category><![CDATA[inflammation]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=710</guid>
		<description><![CDATA[When grief makes you sick: Bereavement induced systemic inflammation is a question of genotype Authors: Schultze-Florey CR, Mart&#237;nez-Maza O, Magpantay L, Breen EC, Irwin MR, G&#252;ndel H, O&#8217;Connor MFBrain Behav Immun. 2012 Jun 23; Abstract Although bereavement is associated with increased morbidity and mortality in the surviving spouse, some widow(er)s remain healthy.&#160;Genetic variability in expression [...]]]></description>
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		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Dopamine Dysfunction in Schizophrenia</title>
		<link>http://www.definitivemind.com/2012/08/16/the-nature-of-dopamine-dysfunction-in-schizophrenia/</link>
		<comments>http://www.definitivemind.com/2012/08/16/the-nature-of-dopamine-dysfunction-in-schizophrenia/#comments</comments>
		<pubDate>Thu, 16 Aug 2012 20:23:57 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Medications]]></category>
		<category><![CDATA[Psychiatry]]></category>
		<category><![CDATA[dopamine]]></category>
		<category><![CDATA[schizophrenia]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=708</guid>
		<description><![CDATA[The Nature of Dopamine Dysfunction in Schizophrenia and What This Means for Treatment: Meta-analysis of Imaging Studies &#160; Arch Gen Psychiatry. 2012 Apr 2; Authors: Howes OD, Kambeitz J, Kim E, Stahl D, Slifstein M, Abi-Dargham A, Kapur S Abstract CONTEXT: Current drug treatments for schizophrenia are inadequate for many patients, and despite 5 decades [...]]]></description>
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		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Type 2 Corticotropin-Releasing Factor Receptor Stimulation Increases Anxiety</title>
		<link>http://www.definitivemind.com/2012/08/16/type-2-corticotropin-releasing-factor-receptor-stimulation-increases-anxiety/</link>
		<comments>http://www.definitivemind.com/2012/08/16/type-2-corticotropin-releasing-factor-receptor-stimulation-increases-anxiety/#comments</comments>
		<pubDate>Thu, 16 Aug 2012 08:29:48 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Neuro-endocrinology]]></category>
		<category><![CDATA[Psychoneuro-immunology]]></category>
		<category><![CDATA[corticotropin]]></category>
		<category><![CDATA[CRF]]></category>
		<category><![CDATA[CRH]]></category>
		<category><![CDATA[hormone]]></category>
		<category><![CDATA[releasing factor]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=704</guid>
		<description><![CDATA[Chronic Activation of Corticotropin-Releasing Factor Type 2 Receptors Reveals a Key Role for 5-HT1A Receptor Responsiveness in Mediating Behavioral and Serotonergic Responses to Stressful Challenge. &#160; Biol Psychiatry. 2012 Jun 13; Authors: Neufeld-Cohen A, Kelly PA, Paul ED, Carter RN, Skinner E, Olverman HJ, Vaughan JM, Issler O, Kuperman Y, Lowry CA, Vale WW, Seckl [...]]]></description>
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		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Eye Movement Tests For Schizophrenia</title>
		<link>http://www.definitivemind.com/2012/08/15/eye-movement-tests-can-distinguish-schizophrenia-cases-from-controls/</link>
		<comments>http://www.definitivemind.com/2012/08/15/eye-movement-tests-can-distinguish-schizophrenia-cases-from-controls/#comments</comments>
		<pubDate>Thu, 16 Aug 2012 07:47:15 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Neurology]]></category>
		<category><![CDATA[Psychiatry]]></category>
		<category><![CDATA[eye]]></category>
		<category><![CDATA[schizophrenia]]></category>
		<category><![CDATA[test]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=700</guid>
		<description><![CDATA[Simple Viewing Tests Can Detect Eye Movement Abnormalities That Distinguish Schizophrenia Cases from Controls with Exceptional Accuracy. &#160; Biol Psychiatry. 2012 May 22; Authors: Benson PJ, Beedie SA, Shephard E, Giegling I, Rujescu D, St Clair D Abstract BACKGROUND: We have investigated which eye-movement tests alone and combined can best discriminate schizophrenia cases from control [...]]]></description>
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		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Because They Are Still Ill&#8230;</title>
		<link>http://www.definitivemind.com/2012/08/14/because-they-are-still-ill/</link>
		<comments>http://www.definitivemind.com/2012/08/14/because-they-are-still-ill/#comments</comments>
		<pubDate>Wed, 15 Aug 2012 07:40:41 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Depression]]></category>
		<category><![CDATA[FEATURED]]></category>
		<category><![CDATA[Pharmacology]]></category>
		<category><![CDATA[Psychiatry]]></category>
		<category><![CDATA[Study Design Limitations]]></category>
		<category><![CDATA[depression]]></category>
		<category><![CDATA[rating scales]]></category>
		<category><![CDATA[remission]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=692</guid>
		<description><![CDATA[Why do some depressed outpatients who are in remission according to the Hamilton Depression Rating Scale not consider themselves to be in remission? J Clin Psychiatry. 2012 Jun;73(6):790-5 Authors: Zimmerman M, Martinez JA, Attiullah N, Friedman M, Toba C, Boerescu DA, Rahgeb M Abstract OBJECTIVE: In treatment studies of depression, remission is typically defined narrowly, based [...]]]></description>
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		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Vitamin D Reduces Arterial Stiffness</title>
		<link>http://www.definitivemind.com/2012/08/14/vitamin-d-reduces-arterial-stiffness/</link>
		<comments>http://www.definitivemind.com/2012/08/14/vitamin-d-reduces-arterial-stiffness/#comments</comments>
		<pubDate>Wed, 15 Aug 2012 06:55:16 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[General Medicine]]></category>
		<category><![CDATA[Nutrition]]></category>
		<category><![CDATA[Vitamins, Minerals and Other Nutrients]]></category>
		<category><![CDATA[cardiovascular]]></category>
		<category><![CDATA[vitamin D]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=690</guid>
		<description><![CDATA[Arterial Stiffness and Vitamin D Levels: the Baltimore Longitudinal Study of Aging J Clin Endocrinol Metab. 2012 Jul 5; Authors: Giallauria F, Milaneschi Y, Tanaka T, Maggio M, Canepa M, Elango P, Vigorito C, Lakatta EG, Ferrucci L, Strait J Abstract Context:&#160;The importance of vitamin D for bone health has long been acknowledged. Recent evidence [...]]]></description>
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		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Sitagliptin (Januvia) has antiinflammatory effects</title>
		<link>http://www.definitivemind.com/2012/08/14/sitagliptin-januvia-has-antiinflammatory-effects/</link>
		<comments>http://www.definitivemind.com/2012/08/14/sitagliptin-januvia-has-antiinflammatory-effects/#comments</comments>
		<pubDate>Wed, 15 Aug 2012 06:50:19 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[General Medicine]]></category>
		<category><![CDATA[Neuro-endocrinology]]></category>
		<category><![CDATA[Psychoneuro-immunology]]></category>
		<category><![CDATA[inflammation]]></category>
		<category><![CDATA[januvia]]></category>
		<category><![CDATA[sitagliptin]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=688</guid>
		<description><![CDATA[Sitagliptin Exerts an Antinflammatory Action J Clin Endocrinol Metab. 2012 Jun 28; Authors: Makdissi A, Ghanim H, Vora M, Green K, Abuaysheh S, Chaudhuri A, Dhindsa S, Dandona P Abstract Context: &#160;Sitagliptin is an inhibitor of the enzyme dipeptidyl peptidase-IV (DPP-IV), which degrades the incretins, glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide, and thus, sitagliptin increases [...]]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/08/14/sitagliptin-januvia-has-antiinflammatory-effects/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
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		<title>Inflammatory Illnesses Decrease Vitamin D 25 OH by Increasing Conversion to Vitamin D 25 Dihydroxy</title>
		<link>http://www.definitivemind.com/2012/08/14/interferon-produced-during-pro-inflammatory-illness-increases-conversion-of-vitamin-d-25-oh-to-vitamin-d-25-dihydroxy-the-active-form/</link>
		<comments>http://www.definitivemind.com/2012/08/14/interferon-produced-during-pro-inflammatory-illness-increases-conversion-of-vitamin-d-25-oh-to-vitamin-d-25-dihydroxy-the-active-form/#comments</comments>
		<pubDate>Wed, 15 Aug 2012 06:29:22 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[General Medicine]]></category>
		<category><![CDATA[Neuro-endocrinology]]></category>
		<category><![CDATA[Psychoneuro-immunology]]></category>
		<category><![CDATA[Vitamins, Minerals and Other Nutrients]]></category>
		<category><![CDATA[inflammation]]></category>
		<category><![CDATA[vitamin D]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=686</guid>
		<description><![CDATA[Circulating interferon-&#947; correlates with 1,25(OH)D and the 1,25(OH)D-to-25(OH)D ratio Cytokine. 2012 Jun 14; Authors: Barker T, Martins TB, Kjeldsberg CR, Trawick RH, Hill HR Abstract The mechanism responsible for the decrease in vitamin D status (i.e., plasma or serum 25-hydroxyvitamin D (25(OH)D) concentration) during inflammatory stress is unknown in humans. Interferon (IFN)-&#947; is an inflammatory [...]]]></description>
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		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Resveratrol vs. Brushing and Flossing</title>
		<link>http://www.definitivemind.com/2012/08/14/regular-brushing-flossing-and-the-use-of-mouth-wash-can-do-just-as-well/</link>
		<comments>http://www.definitivemind.com/2012/08/14/regular-brushing-flossing-and-the-use-of-mouth-wash-can-do-just-as-well/#comments</comments>
		<pubDate>Wed, 15 Aug 2012 06:23:40 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[General Medicine]]></category>
		<category><![CDATA[Psychoneuro-immunology]]></category>
		<category><![CDATA[periodontitis]]></category>
		<category><![CDATA[resveratrol]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=684</guid>
		<description><![CDATA[Effect of resveratrol and modulation of cytokine production on human periodontal ligament cells Cytokine. 2012 Jun 28; Authors: Rizzo A, Bevilacqua N, Guida L, Annunziata M, Romano Carratelli C, Paolillo R Abstract &#160; Periodontitis is a multifactorial polymicrobial infection characterized by a destructive inflammatory process. Porphyromonas gingivalis, a Gram-negative anaerobic black-pigmented rod, which produces several [...]]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/08/14/regular-brushing-flossing-and-the-use-of-mouth-wash-can-do-just-as-well/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Flaxseed oil reduces adipocyte size, adipose monocyte chemoattractant protein-1 levels and T-cell infiltration</title>
		<link>http://www.definitivemind.com/2012/08/14/flaxseed-oil-reduces-adipocyte-size-adipose-monocyte-chemoattractant-protein-1-levels-and-t-cell-infiltration/</link>
		<comments>http://www.definitivemind.com/2012/08/14/flaxseed-oil-reduces-adipocyte-size-adipose-monocyte-chemoattractant-protein-1-levels-and-t-cell-infiltration/#comments</comments>
		<pubDate>Wed, 15 Aug 2012 06:17:01 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[General Medicine]]></category>
		<category><![CDATA[Nutrition]]></category>
		<category><![CDATA[Psychoneuro-immunology]]></category>
		<category><![CDATA[Vitamins, Minerals and Other Nutrients]]></category>
		<category><![CDATA[adipocyte]]></category>
		<category><![CDATA[flaxseed]]></category>
		<category><![CDATA[obesity]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=682</guid>
		<description><![CDATA[Dietary flaxseed oil reduces adipocyte size, adipose monocyte chemoattractant protein-1 levels and T-cell infiltration in obese, insulin-resistant rats Cytokine. 2012 Aug;59(2):382-91 Authors: Baranowski M, Enns J, Blewett H, Yakandawala U, Zahradka P, Taylor CG Abstract BACKGROUND: Adipocyte dysfunction is characterized by an increase in adipocyte size and changes to their adipokine profiles. Immune cell infiltration [...]]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/08/14/flaxseed-oil-reduces-adipocyte-size-adipose-monocyte-chemoattractant-protein-1-levels-and-t-cell-infiltration/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
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		<title>Effect of vitamin D(3) on chemokine expression in pulmonary tuberculosis.</title>
		<link>http://www.definitivemind.com/2012/08/14/effect-of-vitamin-d3-on-chemokine-expression-in-pulmonary-tuberculosis/</link>
		<comments>http://www.definitivemind.com/2012/08/14/effect-of-vitamin-d3-on-chemokine-expression-in-pulmonary-tuberculosis/#comments</comments>
		<pubDate>Wed, 15 Aug 2012 06:12:47 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[General Medicine]]></category>
		<category><![CDATA[Vitamins, Minerals and Other Nutrients]]></category>
		<category><![CDATA[cytokines]]></category>
		<category><![CDATA[inflammation]]></category>
		<category><![CDATA[vitamin D]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=680</guid>
		<description><![CDATA[Effect of vitamin D(3) on chemokine expression in pulmonary tuberculosis Cytokine. 2012 Jul 14; Authors: Selvaraj P, Harishankar M, Singh B, Banurekha VV, Jawahar MS Abstract 1,25 Dihydroxy vitamin D(3) (vitamin D(3)) is an immunomodulator and its deficiency has been associated with susceptibility to tuberculosis. We have studied the immunoregulatory role of vitamin D(3) on [...]]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/08/14/effect-of-vitamin-d3-on-chemokine-expression-in-pulmonary-tuberculosis/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Non-alcoholic fatty liver disease is a pro-inflammatory condition</title>
		<link>http://www.definitivemind.com/2012/08/14/non-alcoholic-fatty-liver-disease-is-a-pro-inflammatory-condition/</link>
		<comments>http://www.definitivemind.com/2012/08/14/non-alcoholic-fatty-liver-disease-is-a-pro-inflammatory-condition/#comments</comments>
		<pubDate>Wed, 15 Aug 2012 06:09:44 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[General Medicine]]></category>
		<category><![CDATA[Neuro-endocrinology]]></category>
		<category><![CDATA[Psychoneuro-immunology]]></category>
		<category><![CDATA[inflammation]]></category>
		<category><![CDATA[liver]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=678</guid>
		<description><![CDATA[Evaluation of inflammatory and angiogenic factors in patients with non-alcoholic fatty liver disease Cytokine. 2012 Aug;59(2):442-9 Authors: Coulon S, Francque S, Colle I, Verrijken A, Blomme B, Heindryckx F, De Munter S, Prawitt J, Caron S, Staels B, Van Vlierberghe H, Van Gaal L, Geerts A Abstract The liver is a major target of injury [...]]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/08/14/non-alcoholic-fatty-liver-disease-is-a-pro-inflammatory-condition/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Does this mean Viagra can treat depression?</title>
		<link>http://www.definitivemind.com/2012/08/14/does-this-mean-viagra-can-treat-depression/</link>
		<comments>http://www.definitivemind.com/2012/08/14/does-this-mean-viagra-can-treat-depression/#comments</comments>
		<pubDate>Wed, 15 Aug 2012 06:00:48 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Neuro-endocrinology]]></category>
		<category><![CDATA[Neurology]]></category>
		<category><![CDATA[Psychoneuro-immunology]]></category>
		<category><![CDATA[depression]]></category>
		<category><![CDATA[inflammation]]></category>
		<category><![CDATA[viagra]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=674</guid>
		<description><![CDATA[Sildenafil (Viagra&#174;) down regulates cytokines and prevents demyelination in a cuprizone-induced MS mouse model Cytokine. 2012 Jun 30; Authors: Nunes AK, Rap&#244;so C, Luna RL, Cruz-H&#246;fling MA, Peixoto CA Abstract Sildenafil induces cGMP accumulation through phosphodiesterase-5 (PDE5) inhibition. &#160;cGMP-pathways protect oligodendrocytes and modulate astroglial and microglial reactions. Microglia and astrocytes play an important role in [...]]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/08/14/does-this-mean-viagra-can-treat-depression/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Substitute Autism for this finding:  Poor nutrition at age 3 is associated with schizotypal personality at age 23</title>
		<link>http://www.definitivemind.com/2012/08/14/substitue-autism-for-this-finding-poor-nutrition-at-age-3-is-associated-with-schizotypal-personality-at-age-23/</link>
		<comments>http://www.definitivemind.com/2012/08/14/substitue-autism-for-this-finding-poor-nutrition-at-age-3-is-associated-with-schizotypal-personality-at-age-23/#comments</comments>
		<pubDate>Tue, 14 Aug 2012 13:37:23 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Nutrition]]></category>
		<category><![CDATA[Psychiatry]]></category>
		<category><![CDATA[autism]]></category>
		<category><![CDATA[schizotypal]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=672</guid>
		<description><![CDATA[Poor nutrition at age 3 and schizotypal personality at age 23: the mediating role of age 11 cognitive functioning. &#160; Am J Psychiatry. 2012 Aug 1;169(8):822-30 Authors: Venables PH, Raine A Abstract OBJECTIVE:&#160;Poor prenatal nutrition has been associated with schizophrenia spectrum disorders in the Netherlands and China, and&#160;it has been suggested that perinatal and postnatal [...]]]></description>
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		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>N-acetylcysteine reduces Cannabis Dependence</title>
		<link>http://www.definitivemind.com/2012/08/13/n-acetylcysteine-reduces-cannabis-dependence/</link>
		<comments>http://www.definitivemind.com/2012/08/13/n-acetylcysteine-reduces-cannabis-dependence/#comments</comments>
		<pubDate>Tue, 14 Aug 2012 04:39:55 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Nutrition]]></category>
		<category><![CDATA[Psychiatry]]></category>
		<category><![CDATA[marijuana]]></category>
		<category><![CDATA[NAC]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=670</guid>
		<description><![CDATA[A double-blind randomized controlled trial of N-acetylcysteine in cannabis-dependent adolescents. &#160; Am J Psychiatry. 2012 Aug 1;169(8):805-12 Authors: Gray KM, Carpenter MJ, Baker NL, Desantis SM, Kryway E, Hartwell KJ, McRae-Clark AL, Brady KT Abstract OBJECTIVE: Preclinical findings suggest that the over-the-counter supplement N-acetylcysteine (NAC), via glutamate modulation in the nucleus accumbens, holds promise as [...]]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/08/13/n-acetylcysteine-reduces-cannabis-dependence/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Metformin reduces antipsychotic-induced amenorrhea and weight gain in women with schizophrenia</title>
		<link>http://www.definitivemind.com/2012/08/13/metformin-reduces-antipsychotic-induced-amenorrhea-and-weight-gain-in-women-with-schizophrenia/</link>
		<comments>http://www.definitivemind.com/2012/08/13/metformin-reduces-antipsychotic-induced-amenorrhea-and-weight-gain-in-women-with-schizophrenia/#comments</comments>
		<pubDate>Tue, 14 Aug 2012 04:29:53 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[General Medicine]]></category>
		<category><![CDATA[Neuro-endocrinology]]></category>
		<category><![CDATA[Psychiatry]]></category>
		<category><![CDATA[amenorrhea]]></category>
		<category><![CDATA[Metformin]]></category>
		<category><![CDATA[weight gain]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=668</guid>
		<description><![CDATA[Metformin for treatment of antipsychotic-induced amenorrhea and weight gain in women with first-episode schizophrenia: a double-blind, randomized, placebo-controlled study &#160; Am J Psychiatry. 2012 Aug 1;169(8):813-21 Authors: Wu RR, Jin H, Gao K, Twamley EW, Ou JJ, Shao P, Wang J, Guo XF, Davis JM, Chan PK, Zhao JP Abstract OBJECTIVE: Data on the treatment [...]]]></description>
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		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>DHEA and DHEA-S increase in response to acute psychosocial stress</title>
		<link>http://www.definitivemind.com/2012/08/13/dhea-and-dhea-s-increase-in-response-to-acute-psychosocial-stress/</link>
		<comments>http://www.definitivemind.com/2012/08/13/dhea-and-dhea-s-increase-in-response-to-acute-psychosocial-stress/#comments</comments>
		<pubDate>Mon, 13 Aug 2012 15:18:00 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Neuro-endocrinology]]></category>
		<category><![CDATA[DHEA]]></category>
		<category><![CDATA[response]]></category>
		<category><![CDATA[stress]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=666</guid>
		<description><![CDATA[DHEA and DHEA-S response to acute psychosocial stress in healthy men and women Biol Psychol. 2012 May;90(2):143-9DHEA and DHEA-S response to acute psychosocial stress in healthy men and women. Authors: Lennartsson AK, Kushnir MM, Bergquist J, Jonsdottir IH Abstract This study investigates the effect of acute psychosocial stress on serum concentrations of DHEA and DHEA-S [...]]]></description>
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		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Glucocorticoids Protect Against Effects of Stress on the Amygdala</title>
		<link>http://www.definitivemind.com/2012/08/12/glucocorticoids-protect-against-effects-of-stress-on-the-amygdala/</link>
		<comments>http://www.definitivemind.com/2012/08/12/glucocorticoids-protect-against-effects-of-stress-on-the-amygdala/#comments</comments>
		<pubDate>Mon, 13 Aug 2012 06:45:19 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Neuro-endocrinology]]></category>
		<category><![CDATA[Psychiatry]]></category>
		<category><![CDATA[Psychoneuro-immunology]]></category>
		<category><![CDATA[amygdala]]></category>
		<category><![CDATA[cortisol]]></category>
		<category><![CDATA[glucocorticoid]]></category>
		<category><![CDATA[stress]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=664</guid>
		<description><![CDATA[Glucocorticoids Protect Against the Delayed Behavioral and Cellular Effects of Acute Stress on the Amygdala. Biol Psychiatry. 2012 May 7; Authors: Rao RP, Anilkumar S, McEwen BS, Chattarji S Abstract BACKGROUND: A single episode of acute immobilization stress has previously been shown to trigger a delayed onset of anxiety-like behavior and spinogenesis in the basolateral [...]]]></description>
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		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Antidepressants are still useful &#8211; they increase neurogenesis and angiogenesis</title>
		<link>http://www.definitivemind.com/2012/08/12/antidepressants-are-still-useful-they-increase-neurogenesis-and-angiogenesis/</link>
		<comments>http://www.definitivemind.com/2012/08/12/antidepressants-are-still-useful-they-increase-neurogenesis-and-angiogenesis/#comments</comments>
		<pubDate>Mon, 13 Aug 2012 06:41:03 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Neurobiology]]></category>
		<category><![CDATA[Psychiatry]]></category>
		<category><![CDATA[antidepressants]]></category>
		<category><![CDATA[neurogenesis]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=662</guid>
		<description><![CDATA[Hippocampal Angiogenesis and Progenitor Cell Proliferation Are Increased with Antidepressant Use in Major Depression. &#160; Biol Psychiatry. 2012 May 30; Authors: Boldrini M, Hen R, Underwood MD, Rosoklija GB, Dwork AJ, Mann JJ, Arango V Abstract BACKGROUND: Adult neurogenesis is coupled to angiogenesis in neurogenic niches in the&#160;dentate gyrus (DG)&#160;and increased by antidepressants in rodents. [...]]]></description>
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		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Low Estrogen Predisposes Women to Posttraumatic Stress Disorder.</title>
		<link>http://www.definitivemind.com/2012/08/12/low-estrogen-predisposes-women-to-posttraumatic-stress-disorder/</link>
		<comments>http://www.definitivemind.com/2012/08/12/low-estrogen-predisposes-women-to-posttraumatic-stress-disorder/#comments</comments>
		<pubDate>Mon, 13 Aug 2012 06:30:07 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Hormones]]></category>
		<category><![CDATA[Neuro-endocrinology]]></category>
		<category><![CDATA[Psychiatry]]></category>
		<category><![CDATA[estrogen]]></category>
		<category><![CDATA[PTSD]]></category>
		<category><![CDATA[stress]]></category>
		<category><![CDATA[trauma]]></category>
		<category><![CDATA[women]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=660</guid>
		<description><![CDATA[Estrogen levels are associated with extinction deficits in women with posttraumatic stress disorder. Biol Psychiatry. 2012 Jul 1;72(1):19-24. Epub 2012 Apr 12. Glover EM, Jovanovic T, Mercer KB, Kerley K, Bradley B, Ressler KJ, Norrholm SD. Abstract BACKGROUND:Women are twice as likely to develop posttraumatic stress disorder (PTSD) than men.&#160;As shown in our previous work, [...]]]></description>
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		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Shorter Telomeres in Severe Mental Illness</title>
		<link>http://www.definitivemind.com/2012/08/12/shorter-telomeres-in-severe-mental-illness/</link>
		<comments>http://www.definitivemind.com/2012/08/12/shorter-telomeres-in-severe-mental-illness/#comments</comments>
		<pubDate>Mon, 13 Aug 2012 06:13:38 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[General Medicine]]></category>
		<category><![CDATA[Metabolism]]></category>
		<category><![CDATA[Mind-Body Medicine]]></category>
		<category><![CDATA[Psychiatry]]></category>
		<category><![CDATA[mental illness]]></category>
		<category><![CDATA[telomere]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=658</guid>
		<description><![CDATA[Telomeres and Early-Life Stress: An Overview Biol Psychiatry. 2012 Jul 23;&#160; Authors: Price LH, Kao HT, Burgers DE, Carpenter LL, Tyrka AR Abstract The long-term sequelae of adverse early-life experiences have long been a focus in psychiatry, with a historic neurobiological emphasis on physiological systems that are demonstrably stress-responsive, such as the hypothalamic-pituitary-adrenal axis and [...]]]></description>
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		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Thyroid Hormone Enhances Nitric Oxide-Mediated Bacterial Clearance and Promotes Survival after Meningococcal Infection</title>
		<link>http://www.definitivemind.com/2012/08/11/thyroid-hormone-enhances-nitric-oxide-mediated-bacterial-clearance-and-promotes-survival-after-meningococcal-infection/</link>
		<comments>http://www.definitivemind.com/2012/08/11/thyroid-hormone-enhances-nitric-oxide-mediated-bacterial-clearance-and-promotes-survival-after-meningococcal-infection/#comments</comments>
		<pubDate>Sat, 11 Aug 2012 16:46:03 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[General Medicine]]></category>
		<category><![CDATA[Hormones]]></category>
		<category><![CDATA[Neuro-endocrinology]]></category>
		<category><![CDATA[bacteria]]></category>
		<category><![CDATA[hormone]]></category>
		<category><![CDATA[infection]]></category>
		<category><![CDATA[nitric oxide]]></category>
		<category><![CDATA[thyroid]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=656</guid>
		<description><![CDATA[Thyroid Hormone Enhances Nitric Oxide-Mediated Bacterial Clearance and Promotes Survival after Meningococcal Infection PLoS One. 2012;7(7):e41445. Epub 2012 Jul 23. Chen Y, Sj&#246;linder M, Wang X, Altenbacher G, Hagner M, Berglund P, Gao Y, Lu T, Jonsson AB, Sj&#246;linder H. Abstract Euthyroid sick syndrome characterized by reduced levels of thyroid hormones (THs) is observed in [...]]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/08/11/thyroid-hormone-enhances-nitric-oxide-mediated-bacterial-clearance-and-promotes-survival-after-meningococcal-infection/feed/</wfw:commentRss>
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		</item>
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		<title>Mirtazapine Inhibits Tumor Growth via Immune Response and Serotonergic System</title>
		<link>http://www.definitivemind.com/2012/08/11/mirtazapine-inhibits-tumor-growth-via-immune-response-and-serotonergic-system/</link>
		<comments>http://www.definitivemind.com/2012/08/11/mirtazapine-inhibits-tumor-growth-via-immune-response-and-serotonergic-system/#comments</comments>
		<pubDate>Sat, 11 Aug 2012 16:35:48 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[General Medicine]]></category>
		<category><![CDATA[Psychoneuro-immunology]]></category>
		<category><![CDATA[cancer]]></category>
		<category><![CDATA[immune]]></category>
		<category><![CDATA[mirtazapine]]></category>
		<category><![CDATA[serotonin]]></category>
		<category><![CDATA[tumor]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=654</guid>
		<description><![CDATA[Mirtazapine Inhibits Tumor Growth via Immune Response and Serotonergic System PLoS One. 2012;7(7):e38886. Epub 2012 Jul 13.Fang CK, Chen HW, Chiang IT, Chen CC, Liao JF, Su TP, Tung CY, Uchitomi Y, Hwang JJ. Abstract To study the tumor inhibition effect of mirtazapine, a drug for patients with depression, CT26/luc colon carcinoma-bearing animal model was [...]]]></description>
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		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Dose-Dependent Effects of Endotoxin on Neurobehavioral Functions in Humans</title>
		<link>http://www.definitivemind.com/2012/08/11/dose-dependent-effects-of-endotoxin-on-neurobehavioral-functions-in-humans/</link>
		<comments>http://www.definitivemind.com/2012/08/11/dose-dependent-effects-of-endotoxin-on-neurobehavioral-functions-in-humans/#comments</comments>
		<pubDate>Sat, 11 Aug 2012 16:25:45 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Psychiatry]]></category>
		<category><![CDATA[behavior]]></category>
		<category><![CDATA[endotoxin]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=652</guid>
		<description><![CDATA[Dose-Dependent Effects of Endotoxin on Neurobehavioral Functions in Humans PLoS One. 2011;6(12):e28330. Epub 2011 Dec 2. Grigoleit JS, Kullmann JS, Wolf OT, Hammes F, Wegner A, Jablonowski S, Engler H, Gizewski E, Oberbeck R, Schedlowski M. Abstract Clinical and experimental evidence document that inflammation and increased peripheral cytokine levels are associated with depression-like symptoms and [...]]]></description>
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		<slash:comments>0</slash:comments>
		</item>
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		<title>African-Americans Need 4000 IU a day of Vitamin D3 to Eliminate Vitamin D 25 OH Disparity with Caucasians.</title>
		<link>http://www.definitivemind.com/2012/08/11/african-americans-need-4000-iu-a-day-of-vitamin-d3-to-eliminate-vitamin-d-25-oh-disparity-with-caucasians/</link>
		<comments>http://www.definitivemind.com/2012/08/11/african-americans-need-4000-iu-a-day-of-vitamin-d3-to-eliminate-vitamin-d-25-oh-disparity-with-caucasians/#comments</comments>
		<pubDate>Sat, 11 Aug 2012 15:39:50 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[General Medicine]]></category>
		<category><![CDATA[Nutrition]]></category>
		<category><![CDATA[Vitamins, Minerals and Other Nutrients]]></category>
		<category><![CDATA[African-American]]></category>
		<category><![CDATA[Caucasian]]></category>
		<category><![CDATA[vitamin D3]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=650</guid>
		<description><![CDATA[Vitamin D3 supplementation (4000 IU/d for 1 y) eliminates differences in circulating 25-hydroxyvitamin D between African American and white men. &#160; Am J Clin Nutr. 2012 Aug;96(2):332-6 Authors: Garrett-Mayer E, Wagner CL, Hollis BW, Kindy MS, Gattoni-Celli S Abstract BACKGROUND: African Americans suffer disproportionately from diabetes and cardiovascular disease and are significantly more likely to [...]]]></description>
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		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Vitamin B6 (pyridoxal-5&#8242;-phosphate) Lowers Risk for Heart Disease, Obesity, and Diabetes</title>
		<link>http://www.definitivemind.com/2012/08/11/vitamin-b6-pyridoxal-5-phosphate-lowers-risk-for-heart-disease-obesity-and-diabetes/</link>
		<comments>http://www.definitivemind.com/2012/08/11/vitamin-b6-pyridoxal-5-phosphate-lowers-risk-for-heart-disease-obesity-and-diabetes/#comments</comments>
		<pubDate>Sat, 11 Aug 2012 15:31:29 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[General Medicine]]></category>
		<category><![CDATA[Nutrition]]></category>
		<category><![CDATA[Vitamins, Minerals and Other Nutrients]]></category>
		<category><![CDATA[diabetes]]></category>
		<category><![CDATA[heart disease]]></category>
		<category><![CDATA[obesity]]></category>
		<category><![CDATA[vitamin B6]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=648</guid>
		<description><![CDATA[Association of vitamin B-6 status with inflammation, oxidative stress, and chronic inflammatory conditions: the Boston Puerto Rican Health Study. &#160; Am J Clin Nutr. 2010 Feb;91(2):337-42 Authors: Shen J, Lai CQ, Mattei J, Ordovas JM, Tucker KL BACKGROUND: Low vitamin B-6 status has been linked to an increased risk of cardiovascular diseases. The cardioprotective effects [...]]]></description>
		<wfw:commentRss>http://www.definitivemind.com/2012/08/11/vitamin-b6-pyridoxal-5-phosphate-lowers-risk-for-heart-disease-obesity-and-diabetes/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Saturated Fat Reduces Risk for Stroke</title>
		<link>http://www.definitivemind.com/2010/08/19/saturated-fat-reduces-risk-for-stroke/</link>
		<comments>http://www.definitivemind.com/2010/08/19/saturated-fat-reduces-risk-for-stroke/#comments</comments>
		<pubDate>Thu, 19 Aug 2010 20:45:27 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[General Medicine]]></category>
		<category><![CDATA[Nutrition]]></category>
		<category><![CDATA[fat]]></category>
		<category><![CDATA[saturated]]></category>
		<category><![CDATA[stroke]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=641</guid>
		<description><![CDATA[Dietary intake of saturated fatty acids and mortality from cardiovascular disease in Japanese: the Japan Collaborative Cohort Study for Evaluation of Cancer Risk Study? Yamagishi K, Iso H, Yatsuya H, Tanabe N, Date C, Kikuchi S, Yamamoto A, Inaba Y, Tamakoshi A; for the JACC Study Group. Am J Clin Nutr. 2010 Aug 4.&#65279; &#160; [...]]]></description>
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		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Microglial Mutation contributes to obsessive-compulsive behavior</title>
		<link>http://www.definitivemind.com/2010/08/01/microglial-mutation-contributes-to-obsessive-compulsive-behavior/</link>
		<comments>http://www.definitivemind.com/2010/08/01/microglial-mutation-contributes-to-obsessive-compulsive-behavior/#comments</comments>
		<pubDate>Mon, 02 Aug 2010 06:47:52 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Neurobiology]]></category>
		<category><![CDATA[Psychiatry]]></category>
		<category><![CDATA[Psychoneuro-immunology]]></category>
		<category><![CDATA[microglia]]></category>
		<category><![CDATA[obsessive-compulsive]]></category>
		<category><![CDATA[OCD]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=632</guid>
		<description><![CDATA[&#160; &#65279; Hematopoietic origin of pathological grooming in Hoxb8 mutant mice. Chen SK,&#160;Tvrdik P,&#160;Peden E,&#160;Cho S,&#160;Wu S,&#160;Spangrude G,&#160;Capecchi MR. Cell. 2010 May 28;141(5):775-85. &#160; Mouse Hoxb8 mutants show unexpected behavior manifested by compulsive grooming and hair removal, similar to behavior in humans with the obsessive-compulsive disorder spectrum disorder trichotillomania. &#160; As Hox gene disruption often [...]]]></description>
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		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Vitamin K reduces Insulin Resistance</title>
		<link>http://www.definitivemind.com/2010/07/30/vitamin-k-reduces-insulin-resistance/</link>
		<comments>http://www.definitivemind.com/2010/07/30/vitamin-k-reduces-insulin-resistance/#comments</comments>
		<pubDate>Sat, 31 Jul 2010 07:43:10 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[General Medicine]]></category>
		<category><![CDATA[Neuro-endocrinology]]></category>
		<category><![CDATA[Nutrition]]></category>
		<category><![CDATA[Psychoneuro-immunology]]></category>
		<category><![CDATA[Vitamins, Minerals and Other Nutrients]]></category>
		<category><![CDATA[diabetes]]></category>
		<category><![CDATA[insulin]]></category>
		<category><![CDATA[resistance]]></category>
		<category><![CDATA[vitamin K]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=611</guid>
		<description><![CDATA[Effect of vitamin K supplementation on insulin resistance in older men and women. Yoshida M, Jacques PF, Meigs JB, Saltzman E, Shea MK, Gundberg C, Dawson-Hughes B, Dallal G, Booth SL. Diabetes Care. 2008 Nov;31(11):2092-6. Epub 2008 Aug 12. OBJECTIVE: Vitamin K has a potentially beneficial role in insulin resistance, but evidence is limited in [...]]]></description>
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		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>The Usefulness of TSH</title>
		<link>http://www.definitivemind.com/2010/07/24/the-usefulness-of-tsh/</link>
		<comments>http://www.definitivemind.com/2010/07/24/the-usefulness-of-tsh/#comments</comments>
		<pubDate>Sat, 24 Jul 2010 17:26:28 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Hormones]]></category>
		<category><![CDATA[Neuro-endocrinology]]></category>
		<category><![CDATA[hormone]]></category>
		<category><![CDATA[thyroid]]></category>
		<category><![CDATA[TSH]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=590</guid>
		<description><![CDATA[Effect of Exogenous Thyroid Hormone Intake on the Interpretation of Serum TSH Test Results: http://www.thyroidscience.com/ hypotheses/ warmingham.2010 /warmingham.intro.7.2010.htm Here is the free PDF: http://www.thyroidscience.com/ hypotheses/ warmingham.2010/ warmingham.7.18.10.pdf I prefer monitoring actual thyroid hormone levels in addition to TSH (Thyroid Stimulating Hormone) for assessment and treatment, rather than relying on TSH alone. One major factor is that there [...]]]></description>
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		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Reducing dietary sodium: the case for caution.</title>
		<link>http://www.definitivemind.com/2010/02/21/reducing-dietary-sodium-the-case-for-caution/</link>
		<comments>http://www.definitivemind.com/2010/02/21/reducing-dietary-sodium-the-case-for-caution/#comments</comments>
		<pubDate>Sun, 21 Feb 2010 09:34:06 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Complementary Medicine]]></category>
		<category><![CDATA[Nutrition]]></category>
		<category><![CDATA[Psychiatry]]></category>
		<category><![CDATA[TOPICS]]></category>
		<category><![CDATA[Vitamins, Minerals and Other Nutrients]]></category>
		<category><![CDATA[salt]]></category>
		<category><![CDATA[sodium]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=573</guid>
		<description><![CDATA[Reducing dietary sodium: the case for caution. JAMA. 2010 Feb 3;303(5):448-9 Authors: Alderman MH QUOTE: Multiple randomized clinical trials (RCTs) have established that reduction of sodium intake sufficient to lower blood pressure also increases sympathetic nerve activity, decreases insulin sensitivity, activates the renin angiotensin system, and stimulates aldosterone secretion. &#8212;&#8212;&#8212;- Low salt diets lead to: [...]]]></description>
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		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Low Serum Folate Levels as a Risk Factor for Depression</title>
		<link>http://www.definitivemind.com/2010/02/21/low-serum-folate-levels-as-a-risk-factor-for-depression/</link>
		<comments>http://www.definitivemind.com/2010/02/21/low-serum-folate-levels-as-a-risk-factor-for-depression/#comments</comments>
		<pubDate>Sun, 21 Feb 2010 08:50:34 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Complementary Medicine]]></category>
		<category><![CDATA[Nutrition]]></category>
		<category><![CDATA[Psychiatry]]></category>
		<category><![CDATA[Vitamins, Minerals and Other Nutrients]]></category>
		<category><![CDATA[depression]]></category>
		<category><![CDATA[folic acid]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=571</guid>
		<description><![CDATA[Low Serum Folate Levels as a Risk Factor for Depressive Mood in Patients With Chronic Epilepsy J Neuropsychiatry Clin Neurosci 15:64-66, February 2003 Johannes Rösche, Dr.med., M.A., Carmen Uhlmann, Dr.hum.biol., Dipl.Psych. and Walter Fröscher, Prof.Dr.med. This study takes into consideration whether low serum folate levels may contribute to depressive mood in patients with chronic epilepsy. [...]]]></description>
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		</item>
		<item>
		<title>Hydrocortisone treatment restores brain metabolism and working memory in PTSD</title>
		<link>http://www.definitivemind.com/2010/02/20/hydrocortisone-treatment-restores-brain-metabolism-and-working-memory-in-ptsd/</link>
		<comments>http://www.definitivemind.com/2010/02/20/hydrocortisone-treatment-restores-brain-metabolism-and-working-memory-in-ptsd/#comments</comments>
		<pubDate>Sun, 21 Feb 2010 07:17:28 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Hormones]]></category>
		<category><![CDATA[Neuro-endocrinology]]></category>
		<category><![CDATA[Psychiatry]]></category>
		<category><![CDATA[cortisol]]></category>
		<category><![CDATA[hydrocortisone]]></category>
		<category><![CDATA[PTSD]]></category>
		<category><![CDATA[stress]]></category>
		<category><![CDATA[trauma]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=569</guid>
		<description><![CDATA[Changes in Relative Glucose Metabolic Rate Following Cortisol Administration in Aging Veterans with Posttraumatic Stress Disorder: An FDG-PET Neuroimaging Study J Neuropsychiatry Clin Neurosci.2009; 21: 132-143 Rachel Yehuda, Ph.D., Philip D. Harvey, Ph.D., Julia A. Golier, M.D., Randall E. Newmark, B.A., Christopher R. Bowie, Ph.D., Janelle J. Wohltmann, B.A., Robert A. Grossman, M.D., James Schmeidler, [...]]]></description>
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		</item>
		<item>
		<title>DHEA improves immune system response against parasites</title>
		<link>http://www.definitivemind.com/2010/02/20/dhea-improves-immune-system-response-against-parasites/</link>
		<comments>http://www.definitivemind.com/2010/02/20/dhea-improves-immune-system-response-against-parasites/#comments</comments>
		<pubDate>Sun, 21 Feb 2010 06:51:49 +0000</pubDate>
		<dc:creator>Romeo Mariano MD</dc:creator>
				<category><![CDATA[Hormones]]></category>
		<category><![CDATA[Neuro-endocrinology]]></category>
		<category><![CDATA[Psychoneuro-immunology]]></category>
		<category><![CDATA[TOPICS]]></category>
		<category><![CDATA[DHEA]]></category>
		<category><![CDATA[immune system]]></category>
		<category><![CDATA[parasites]]></category>

		<guid isPermaLink="false">http://www.definitivemind.com/?p=567</guid>
		<description><![CDATA[Effects of dehydroepiandrosterone-sulfate (DHEA-S) and benznidazole treatments during acute infection of two different Trypanosoma cruzi strains. Immunobiology. 2010 Feb 15; Authors: Domingues Santos C, Loria RM, Rodrigues Oliveira LG, Collins Kuehn C, Alonso Toldo MP, Albuquerque S, do Prado Júnior JC A significant role for hormones in regulating the balance of Th1- and Th2-associated cytokines [...]]]></description>
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		<slash:comments>0</slash:comments>
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