Category: Psychology
Stress Activates Immune System Pro-inflammatory Changes Contributing to Coronary Artery Disease
The evidence for the effects of acute and chronic psychological stress on the onset and progression of CAD is consistent and convincing. Psychological stressors change endothelial function and lead to chemotaxis. Acute psychological stressors lead to leukocytosis, increased natural killer cell cytotoxicity and reduced proliferative response to mitogens. Psychological stressors will increase haemostatic factors and acute phase proteins, possibly leading to thrombus formation and myocardial infarction.
Brief Wakeful Resting Boosts Memory Consolidation and Retention
Brief Wakeful Resting Boosts New Memories Over the Long Term Psychol Sci. 2012 Jul 24; Dewar M, Alber J, Butler C, Cowan N, Della Sala S Abstract A brief wakeful rest after new verbal learning enhances memory for several minutes. In the research reported here, we explored the possibility of extending this rest-induced memory enhancement [...]
Celebrex is a Potent Antidepressant
Effect of celecoxib add-on treatment on symptoms and serum IL-6 concentrations in patients with major depressive disorder: Randomized double-blind placebo-controlled study J Affect Disord. 2012 Apr 18; Authors: Abbasi SH, Hosseini F, Modabbernia A, Ashrafi M, Akhondzadeh S Abstract BACKGROUND: It has been proposed that the mechanism of the antidepressant effect of celecoxib is linked [...]
Chronic psychosocial stress triggers cognitive impairment in Alzheimer’s disease
Chronic psychosocial stress triggers cognitive impairment in a novel at-risk model of Alzheimer’s disease Neurobiology of Disease, In Press, Accepted Manuscript, Available online 4 January 2010Trinh T., Tran , Marisa, Srivareerat , Karim A., Alkadhi Abstract Although it is generally accepted that Aβ contributes to the pathogenesis of Alzheimer’s disease (AD), other factors that impact [...]
Abuse in childhood linked to migraine and other pain disorders
(Via EurekAlert! – Breaking News.) Abuse in childhood linked to migraine and other pain disorders: “Researchers from the American Headache Society’s Women’s Issues Section Research Consortium found that incidence of childhood maltreatment, especially emotional abuse and neglect, are prevalent in migraine patients. Full findings of the study appear in the January issue of Headache: The [...]
Neural Network Underlying Acute Grief is the Same as the Neural Network Underlying Physical Pain
Neural Activation Underlying Acute Grief in Women After the Loss of an Unborn Child [Articles]: Am J Psychiatry 2009; 166:1402-1410 (published online November 2, 2009; doi: 10.1176/appi.ajp.2009.08121875) Anette Kersting, M.D., Patricia Ohrmann, M.D., Anya Pedersen, Ph.D., Kristin Kroker, Ph.D., Daniela Samberg, M.D., Jochen Bauer, M.Sc., Harald Kugel, Ph.D., Katja Koelkebeck, M.D., Johannes Steinhard, M.D., Walter [...]
Childhood Physical Abuse Increases the Risk for Cancer
In a recent study, childhood physical abuse increased the risk of developing cancer by 40%. What are the potential mechanisms? Here are my thoughts: Traumatic events such as childhood physical abuse may lead to chronic hypothalamic-pituitary-adrenal dysregulation with low cortisol production. This is seen particularly in those suffering from posttraumatic stress disorder or anxiety disorders [...]
