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Stress Activates Immune System Pro-inflammatory Changes Contributing to Coronary Artery Disease

| 2012.10.06

The evidence for the effects of acute and chronic psychological stress on the onset and progression of CAD is consistent and convincing. Psychological stressors change endothelial function and lead to chemotaxis. Acute psychological stressors lead to leukocytosis, increased natural killer cell cytotoxicity and reduced proliferative response to mitogens. Psychological stressors will increase haemostatic factors and acute phase proteins, possibly leading to thrombus formation and myocardial infarction.

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Yogic Meditation Reduces Inflammation By Reducing NF-κB and Increasing IRF -related Gene Transcription of Pro-inflammatory Cytokines

| 2012.09.01

Yogic meditation reverses NF-κB and IRF-related transcriptome dynamics in leukocytes of family dementia caregivers in a randomized controlled trial Psychoneuroendocrinology. 2012 Jul 13; Black DS, Cole SW, Irwin MR, Breen E, St Cyr NM, Nazarian N, Khalsa DS, Lavretsky H Abstract BACKGROUND: Although yoga and meditation have been used for stress reduction with reported improvement [...]

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Brief Wakeful Resting Boosts Memory Consolidation and Retention

| 2012.09.01

Brief Wakeful Resting Boosts New Memories Over the Long Term Psychol Sci. 2012 Jul 24; Dewar M, Alber J, Butler C, Cowan N, Della Sala S Abstract A brief wakeful rest after new verbal learning enhances memory for several minutes. In the research reported here, we explored the possibility of extending this rest-induced memory enhancement [...]

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The Problem of Meta-Analysis of Psychotherapy’s Effect on Suicidality

| 2012.08.24

The effects of psychotherapy for adult depression on suicidality and hopelessness: A systematic review and meta-analysis J Affect Disord. 2012 Jul 23; Authors: Cuijpers P, de Beurs DP, van Spijker BA, Berking M, Andersson G, Kerkhof AJ Abstract BACKGROUND: Although treatment guidelines suggest that suicidal patients with depression should be treated for depression with psychotherapy, [...]

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Celebrex is a Potent Antidepressant

| 2012.08.23

Effect of celecoxib add-on treatment on symptoms and serum IL-6 concentrations in patients with major depressive disorder: Randomized double-blind placebo-controlled study J Affect Disord. 2012 Apr 18; Authors: Abbasi SH, Hosseini F, Modabbernia A, Ashrafi M, Akhondzadeh S Abstract BACKGROUND: It has been proposed that the mechanism of the antidepressant effect of celecoxib is linked [...]

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Oxytocin Enhances Adaptive Response to Social Stress

| 2012.08.17

A heartfelt response: Oxytocin effects on response to social stress in men and women   Biol Psychol. 2012 Apr;90(1):1-9 Authors: Kubzansky LD, Mendes WB, Appleton AA, Block J, Adler GK Abstract BACKGROUND: Animal research indicates that oxytocin is involved in social behavior, stress regulation, and positive physiologic adaptation. This study examines whether oxytocin enhances adaptive [...]

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Chronic psychosocial stress triggers cognitive impairment in Alzheimer’s disease

| 2010.01.10 | 0 Comments

Chronic psychosocial stress triggers cognitive impairment in a novel at-risk model of Alzheimer’s disease Neurobiology of Disease, In Press, Accepted Manuscript, Available online 4 January 2010Trinh T., Tran , Marisa, Srivareerat , Karim A., Alkadhi Abstract Although it is generally accepted that Aβ contributes to the pathogenesis of Alzheimer’s disease (AD), other factors that impact [...]

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Abuse in childhood linked to migraine and other pain disorders

| 2010.01.06 | 0 Comments

(Via EurekAlert! – Breaking News.) Abuse in childhood linked to migraine and other pain disorders: “Researchers from the American Headache Society’s Women’s Issues Section Research Consortium found that incidence of childhood maltreatment, especially emotional abuse and neglect, are prevalent in migraine patients. Full findings of the study appear in the January issue of Headache: The [...]

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Neural Network Underlying Acute Grief is the Same as the Neural Network Underlying Physical Pain

| 2010.01.04 | 0 Comments

Neural Activation Underlying Acute Grief in Women After the Loss of an Unborn Child [Articles]: Am J Psychiatry 2009; 166:1402-1410 (published online November 2, 2009; doi: 10.1176/appi.ajp.2009.08121875) Anette Kersting, M.D., Patricia Ohrmann, M.D., Anya Pedersen, Ph.D., Kristin Kroker, Ph.D., Daniela Samberg, M.D., Jochen Bauer, M.Sc., Harald Kugel, Ph.D., Katja Koelkebeck, M.D., Johannes Steinhard, M.D., Walter [...]

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Childhood Physical Abuse Increases the Risk for Cancer

| 2009.06.26

In a recent study, childhood physical abuse increased the risk of developing cancer by 40%. What are the potential mechanisms? Here are my thoughts: Traumatic events such as childhood physical abuse may lead to chronic hypothalamic-pituitary-adrenal dysregulation with low cortisol production. This is seen particularly in those suffering from posttraumatic stress disorder or anxiety disorders [...]

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