From the category archives:

Psychology

Chronic psychosocial stress triggers cognitive impairment in Alzheimer’s disease

by Romeo Mariano, MD (January 10, 2010)

Chronic psychosocial stress triggers cognitive impairment in a novel at-risk model of Alzheimer’s disease
Neurobiology of Disease, In Press, Accepted Manuscript, Available online 4 January 2010Trinh T., Tran , Marisa, Srivareerat , Karim A., Alkadhi
Abstract
Although it is generally accepted that Aβ contributes to the pathogenesis of Alzheimer’s disease (AD), other factors that impact the [...]

0 comments

Abuse in childhood linked to migraine and other pain disorders

by Romeo Mariano, MD (January 6, 2010)

(Via EurekAlert! - Breaking News.)
Abuse in childhood linked to migraine and other pain disorders: “Researchers from the American Headache Society’s Women’s Issues Section Research Consortium found that incidence of childhood maltreatment, especially emotional abuse and neglect, are prevalent in migraine patients. Full findings of the study appear in the January issue of Headache: The [...]

0 comments

Neural Network Underlying Acute Grief is the Same as the Neural Network Underlying Physical Pain

by Romeo Mariano, MD (January 4, 2010)

Neural Activation Underlying Acute Grief in Women After the Loss of an Unborn Child [Articles]:

Am J Psychiatry 2009; 166:1402-1410 (published online November 2, 2009; doi: 10.1176/appi.ajp.2009.08121875)
Anette Kersting, M.D., Patricia Ohrmann, M.D., Anya Pedersen, Ph.D., Kristin Kroker, Ph.D., Daniela Samberg, M.D., Jochen Bauer, M.Sc., Harald Kugel, Ph.D., Katja Koelkebeck, M.D., Johannes Steinhard, M.D., Walter Heindel, M.D., [...]

0 comments

Childhood Physical Abuse Increases the Risk for Cancer

by Romeo Mariano, MD (June 26, 2009)

In a recent study, childhood physical abuse increased the risk of developing cancer by 40%. What are the potential mechanisms? Here are my thoughts:
Traumatic events such as childhood physical abuse may lead to chronic hypothalamic-pituitary-adrenal dysregulation with low cortisol production. This is seen particularly in those suffering from posttraumatic stress disorder or [...]