From the category archives:

Hormone Replacement Therapy

Hydrocortisone treatment restores brain metabolism and working memory in PTSD

by Romeo Mariano, MD (February 20, 2010)

Changes in Relative Glucose Metabolic Rate Following Cortisol Administration in Aging Veterans with Posttraumatic Stress Disorder: An FDG-PET Neuroimaging Study
J Neuropsychiatry Clin Neurosci.2009; 21: 132-143
Rachel Yehuda, Ph.D., Philip D. Harvey, Ph.D., Julia A. Golier, M.D., Randall E. Newmark, B.A., Christopher R. Bowie, Ph.D., Janelle J. Wohltmann, B.A., Robert A. Grossman, M.D., James Schmeidler, Ph.D., [...]

DHEA improves immune system response against parasites

by Romeo Mariano, MD (February 20, 2010)

Effects of dehydroepiandrosterone-sulfate (DHEA-S) and benznidazole treatments during acute infection of two different Trypanosoma cruzi strains.

Immunobiology. 2010 Feb 15;
Authors: Domingues Santos C, Loria RM, Rodrigues Oliveira LG, Collins Kuehn C, Alonso Toldo MP, Albuquerque S, do Prado Júnior JC
A significant role for hormones in regulating the balance of Th1- and Th2-associated cytokines with [...]

Testosterone improves Muscle Strength, Physical Function, Body Composition, and Quality of Life in Intermediate-Frail and Frail Elderly Men

by Romeo Mariano, MD (January 18, 2010)

Effects of Testosterone on Muscle Strength, Physical Function, Body Composition, and Quality of Life in Intermediate-Frail and Frail Elderly Men: A Randomized, Double-Blind, Placebo-Controlled Study.
J Clin Endocrinol Metab. 2010 Jan 8;
Authors: Srinivas-Shankar U, Roberts SA, Connolly MJ, O’ Connell MD, Adams JE, Oldham JA, Wu FC
Context: Physical frailty is associated with reduced muscle strength, [...]

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Testosterone for Migraine

by Romeo Mariano, MD (January 16, 2010)

Androgenic suppression of spreading depression in familial hemiplegic migraine type 1 mutant mice.

Ann Neurol. 2009 Oct;66(4):564-8
Authors: Eikermann-Haerter K, Baum MJ, Ferrari MD, van den Maagdenberg AM, Moskowitz MA, Ayata C
Familial hemiplegic migraine type 1 (FHM1), a severe migraine with aura variant, is caused by mutations in the CACNA1A gene.
Mutant mice carrying [...]

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Endocrine consequences of opioid therapy.

by Romeo Mariano, MD (January 14, 2010)

Endocrine consequences of opioid therapy.
Psychoneuroendocrinology. 2009 Dec;34 Suppl 1:S162-8
Authors: Aloisi AM, Aurilio C, Bachiocco V, Biasi G, Fiorenzani P, Pace MC, Paci V, Pari G, Passavanti G, Ravaioli L, Sindaco G, Vellucci R, Ceccarelli I
Gonadal hormones are known to be affected by morphine and other opioids. In this paper, we summarize data collected in [...]

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To Sleep, Perchance to Reset Your Body Clock

by Romeo Mariano, MD (January 11, 2010)

To Sleep, Perchance to Reset Your Body Clock
January 9, 2010 Psychiatric Times. Vol. 27 No. 2
Alfred J. Lewy, MD, PhD
Dr Lewy is professor of psychiatry, ophthalmology, and physiology/pharmacology, senior vice chairman of the department of psychiatry, and director of the sleep and mood disorders laboratory at the Oregon Health & Science University, Portland.
He wrote [...]

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Testosterone Augmentation Therapy Reduces Major Depressive Disorder Severity

by Romeo Mariano, MD (January 10, 2010)

Low-dose Transdermal Testosterone Augmentation Therapy Improves Depression Severity in Women
Karen K. Miller, MD, Roy H. Perlis, MD, MSc, George I. Papakostas, MD, David Mischoulon, MD, PhD, Dan V. Iosifescu, MD, MSc, Danielle J. Brick, BA, and Maurizio Fava, MD
CNS Spectr. 2009;14(12):688-694
[download PDF]
Background: Inadequate response to antidepressant monotherapy in women with major depressive disorder is [...]

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Chronic stress on memory decline in cognitively normal and mildly impaired older adults. Protective effects of Cortisol signaling.

by Romeo Mariano, MD (January 4, 2010)

Effects of chronic stress on memory decline in cognitively normal and mildly impaired older adults.: “

Effects of chronic stress on memory decline in cognitively normal and mildly impaired older adults.
Am J Psychiatry. 2009 Dec;166(12):1384-91
Authors: Peavy GM, Salmon DP, Jacobson MW, Hervey A, Gamst AC, Wolfson T, Patterson TL, Goldman S, Mills PJ, Khandrika [...]

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Vitamin D3 and Curcumin Clears Amyloid Plaques in Alzheimer’s Disease

by Romeo Mariano, MD (July 15, 2009)

Scientists from UCLA, UC Riverside and the Human BioMolecular Research Institute have found that Vitamin D3 together with Curcumin, a substance found in Turmeric Spice, stimulates the immune system to clear the brain of Amyloid Beta, which is found in the plaques of Alzheimer’s Disease.

Hormones and Lab Pointers

by Romeo Mariano, MD (June 20, 2009)

Some pointers from answering a recent post.

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